» Articles » PMID: 28428966

Nutrition and Metabolism in Burn Patients

Overview
Journal Burns Trauma
Date 2017 Apr 22
PMID 28428966
Citations 55
Authors
Affiliations
Soon will be listed here.
Abstract

Severe burn causes significant metabolic derangements that make nutritional support uniquely important and challenging for burned patients. Burn injury causes a persistent and prolonged hypermetabolic state and increased catabolism that results in increased muscle wasting and cachexia. Metabolic rates of burn patients can surpass twice normal, and failure to fulfill these energy requirements causes impaired wound healing, organ dysfunction, and susceptibility to infection. Adequate assessment and provision of nutritional needs is imperative to care for these patients. There is no consensus regarding the optimal timing, route, amount, and composition of nutritional support for burn patients, but most clinicians advocate for early enteral nutrition with high-carbohydrate formulas. Nutritional support must be individualized, monitored, and adjusted throughout recovery. Further investigation is needed regarding optimal nutritional support and accurate nutritional endpoints and goals.

Citing Articles

Trace elements: Clinical perspectives in the critically ill.

Karunakaran V, Harding K, Sarnowski A, Walter E J Intensive Care Soc. 2025; :17511437241305269.

PMID: 39926387 PMC: 11800230. DOI: 10.1177/17511437241305269.


Red blood cell distribution width at admission and the short-term mortality of patients with severe burn injury: a meta-analysis.

Cao Q, He X, Chen X, Han X, Yang L Eur J Med Res. 2024; 29(1):589.

PMID: 39696510 PMC: 11658159. DOI: 10.1186/s40001-024-02165-z.


Toward Precision in Nutrition Therapy.

Stoppe C, Hill A, Christopher K, Kristof A Crit Care Med. 2024; 53(2):e429-e440.

PMID: 39688452 PMC: 11801434. DOI: 10.1097/CCM.0000000000006537.


Nutritional Optimization of the Surgical Patient: A Narrative Review.

Heutlinger O, Acharya N, Tedesco A, Ramesh A, Smith B, Nguyen N Adv Nutr. 2024; 16(1):100351.

PMID: 39617150 PMC: 11784791. DOI: 10.1016/j.advnut.2024.100351.


Beta blockers in critical illness: promising but appropriate subphenotyping is needed.

Zhang L, Ke L Burns Trauma. 2024; 12:tkae060.

PMID: 39355305 PMC: 11442145. DOI: 10.1093/burnst/tkae060.


References
1.
Yu Y, Tompkins R, Ryan C, Young V . The metabolic basis of the increase of the increase in energy expenditure in severely burned patients. JPEN J Parenter Enteral Nutr. 1999; 23(3):160-8. DOI: 10.1177/0148607199023003160. View

2.
Klein G, Herndon D, Chen T, Kulp G, Holick M . Standard multivitamin supplementation does not improve vitamin D insufficiency after burns. J Bone Miner Metab. 2009; 27(4):502-6. PMC: 3857303. DOI: 10.1007/s00774-009-0065-7. View

3.
. ISBI Practice Guidelines for Burn Care. Burns. 2016; 42(5):953-1021. DOI: 10.1016/j.burns.2016.05.013. View

4.
Chao T, Herndon D, Porter C, Chondronikola M, Chaidemenou A, Abdelrahman D . Skeletal Muscle Protein Breakdown Remains Elevated in Pediatric Burn Survivors up to One-Year Post-Injury. Shock. 2015; 44(5):397-401. PMC: 4615533. DOI: 10.1097/SHK.0000000000000454. View

5.
Gottschlich M, Mayes T, Khoury J, Warden G . Significance of obesity on nutritional, immunologic, hormonal, and clinical outcome parameters in burns. J Am Diet Assoc. 1993; 93(11):1261-8. DOI: 10.1016/0002-8223(93)91952-m. View