Ultrastructural Phosphatase Histochemistry of Submandibular and Parotid Salivary Glands of Man

Overview

Journal Histochem J

Specialty Biochemistry

Date 1988 Feb 1

PMID 2839435

Citations 2

Authors

J D Harrison

D W Auger

M S Badir

Affiliations

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Abstract

Thiamine pyrophosphatase was demonstrated in the Golgi complex and acid phosphatase in the GERL of acinar cells of submandibular and parotid glands and were previously demonstrated in cells of intercalary ducts. Thiamine pyrophosphatase was also demonstrated in the Golgi complex of cells of striated and excretory ducts and myoepithelial cells. Acid phosphatase was also demonstrated in lysosomes. Alkaline phosphatase was rarely demonstrated light microscopically at luminal surfaces of striated and excretory ducts and electron microscopically in luminal vesicles in cells of striated ducts. The demonstration of the phosphatases in Golgi complexes and GERLs indicates that investigations on these structures in experimental animals are relevant to human salivary glands and supports the opinion that ductal cells as well as acinar cells secrete organic material. The presence of alkaline phosphatase at luminal surfaces of striated and excretory ducts suggests that resorption as well as secretion may occur in them.

Citing Articles

Thiamine pyrophosphatase activity in secretory cells of the lateral prostate and seminal vesicle of normal and castrated guinea pigs and castrates treated with oestradiol.

Tam C, Wong Y Histochem J. 1993; 25(1):77-85.

PMID: 8432665 DOI: 10.1007/BF00161047.

Ultrastructural observations on luminal structures of pleomorphic adenoma of parotid and submandibular salivary glands of man.

Harrison J, Auger D Virchows Arch A Pathol Anat Histopathol. 1989; 415(6):559-63.

PMID: 2552653 DOI: 10.1007/BF00718650.

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