Reported Exercise-Related Respiratory Symptoms and Exercise-Induced Bronchoconstriction in Asthmatic Children

Overview

Journal J Clin Med Res

Specialty General Medicine

Date 2017 Apr 11

PMID 28392861

Citations 2

Authors

Demet Inci

Refoel Guggenheim

Derya Ufuk Altintas

Johannes H Wildhaber

Alexander Moeller

Affiliations

Soon will be listed here.

Abstract

Background: Unlimited physical activity is one of the key issues of asthma control and management. We investigated how reliable reported exercise-related respiratory symptoms (ERRS) are in predicting exercise-induced bronchoconstriction (EIB) in asthmatic children.

Methods: In this prospective study, 179 asthmatic children aged 7 - 15 years were asked for specific questions on respiratory symptoms related to exercise and allocated into two groups according to whether they complained about symptoms. Group I (n = 134) consisted of children answering "yes" to one or more of the questions and group II (n = 45) consisted of children answering "no" to all of the questions.

Results: Sixty-four of 179 children showed a positive exercise challenge test (ECT). There was no difference in the frequency of a positive test between children in group I (n = 48) and group II (n = 12) (P = 0.47). The sensitivity of a positive report for ERRS to predict a positive ECT was only 37%, with a specificity of 0.72.

Conclusion: According to current guidelines, the report or lack of ERRS has direct consequences on treatment decisions. However, the history of ERRS did not predict EIB and one-third of asthmatic children without complaints of ERRS developed EIB during the ECT. This raises the question of the need for objective measures of bronchial hyperresponsiveness (BHR) in pediatric asthma management.

Citing Articles

An Algorithm for Strategic Continuation or Restriction of Asthma Medication Prior to Exercise Challenge Testing in Childhood Exercise Induced Bronchoconstriction.

Hengeveld V, Keijzer P, Diamant Z, Thio B Front Pediatr. 2022; 10:800193.

PMID: 35273926 PMC: 8902070. DOI: 10.3389/fped.2022.800193.

Assessing Exercise-Induced Bronchoconstriction in Children; The Need for Testing.

Lammers N, van Hoesel M, Kamphuis M, Brusse-Keizer M, van der Palen J, Visser R Front Pediatr. 2019; 7:157.

PMID: 31106184 PMC: 6498950. DOI: 10.3389/fped.2019.00157.

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