» Articles » PMID: 28384276

Short-term Effects of Weather and Air Pollution on Atopic Dermatitis Symptoms in Children: A Panel Study in Korea

Overview
Journal PLoS One
Date 2017 Apr 7
PMID 28384276
Citations 30
Authors
Affiliations
Soon will be listed here.
Abstract

Introduction: The effects of weather and air pollution on the severity and persistence of atopic dermatitis (AD) are important issues that have not been investigated in detail. The objective of our study was to determine the short-term effects of meteorological variables and air pollution on AD symptoms in children.

Methods: We enrolled 177 AD patients with 5 years or younger from the Seoul Metropolitan Area, Korea, and followed for 17 months between August 2013 and December 2014. Symptoms records of 35,158 person-days, including itching, sleep disturbance, erythema, dry skin, oozing, and edema, were obtained. We estimated the effect of meteorological variables including daily mean temperature, relative humidity (RH), diurnal temperature range (DTR), rainfall and air pollutants including particulate matter with an aerodynamic diameter ≤10 μm (PM10), nitrogen dioxide (NO2), and tropospheric ozone (O3) on AD symptoms using a generalized linear mixed model with adjustment for related confounding factors.

Results: A 5°C increase in outdoor temperature and a 5% increase in outdoor RH was associated with 12.8% (95% confidence intervals (CI): 10.5, 15.2) and 3.3% (95% CI: 1.7, 4.7) decrease in AD symptoms, respectively, on the same day. An increase of rainfall by 5 mm increased AD symptoms by 7.3% (95% CI: 3.6, 11.1) for the days with <40 mm rainfall. The risk of AD symptoms increased by 284.9% (95% CI: 67.6, 784.2) according to a 5°C increase in DTR when it was >14°C. An increase in PM10, NO2, and O3 by 10 units increased the risk of AD symptoms on the same day by 3.2% (95% CI: 1.5, 4.9), 5.0% (95% CI: 1.4, 8.8), and 6.1% (95% CI: 3.2, 9.0), respectively.

Conclusion: Exposure to meteorological variables and air pollutants are associated with AD symptoms in young children.

Citing Articles

Particulate Matter and Its Molecular Effects on Skin: Implications for Various Skin Diseases.

Paik K, Na J, Huh C, Shin J Int J Mol Sci. 2024; 25(18).

PMID: 39337376 PMC: 11432173. DOI: 10.3390/ijms25189888.


Association between exposure to ambient air pollution, meteorological factors and atopic dermatitis consultations in Singapore-a stratified nationwide time-series analysis.

Mailepessov D, Ong J, Nasir M, Aik J, Woo M, Zhao X Sci Rep. 2024; 14(1):10320.

PMID: 38710739 PMC: 11074125. DOI: 10.1038/s41598-024-60712-4.


Association between Outdoor and Indoor Air Pollution Sources and Atopic Eczema among Preschool Children in South Africa.

Bhuda M, Wichmann J, Shirinde J Int J Environ Res Public Health. 2024; 21(3).

PMID: 38541325 PMC: 10969843. DOI: 10.3390/ijerph21030326.


Impact of Air Pollution on Atopic Dermatitis: A Comprehensive Review.

Pan Z, Dai Y, Akar-Ghibril N, Simpson J, Ren H, Zhang L Clin Rev Allergy Immunol. 2023; 65(2):121-135.

PMID: 36853525 DOI: 10.1007/s12016-022-08957-7.


Air Pollution and Atopic Dermatitis, from Molecular Mechanisms to Population-Level Evidence: A Review.

Fadadu R, Abuabara K, Balmes J, Hanifin J, Wei M Int J Environ Res Public Health. 2023; 20(3).

PMID: 36767891 PMC: 9916398. DOI: 10.3390/ijerph20032526.


References
1.
Ahn K . The role of air pollutants in atopic dermatitis. J Allergy Clin Immunol. 2014; 134(5):993-9. DOI: 10.1016/j.jaci.2014.09.023. View

2.
Sargen M, Hoffstad O, Margolis D . Warm, humid, and high sun exposure climates are associated with poorly controlled eczema: PEER (Pediatric Eczema Elective Registry) cohort, 2004-2012. J Invest Dermatol. 2013; 134(1):51-57. PMC: 3869874. DOI: 10.1038/jid.2013.274. View

3.
Langan S, Bourke J, Silcocks P, Williams H . An exploratory prospective observational study of environmental factors exacerbating atopic eczema in children. Br J Dermatol. 2006; 154(5):979-80. DOI: 10.1111/j.1365-2133.2006.07153.x. View

4.
Penard-Morand C, Raherison C, Charpin D, Kopferschmitt C, Lavaud F, Caillaud D . Long-term exposure to close-proximity air pollution and asthma and allergies in urban children. Eur Respir J. 2010; 36(1):33-40. DOI: 10.1183/09031936.00116109. View

5.
Kim Y, Zhou Y, Gao Y, Fu J, Johnson B, Huang C . Spatially resolved estimation of ozone-related mortality in the United States under two Representative Concentration Pathways (RCPs) and their uncertainty. Clim Change. 2014; 128(1-2):71-84. PMC: 4267285. DOI: 10.1007/s10584-014-1290-1. View