Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art

Overview

Journal Neural Plast

Specialty Neurology

Date 2017 Apr 5

PMID 28373915

Citations 12

Authors

Marialuisa Gandolfi

Nicola Smania

Antonio Vella

Alessandro Picelli

Salvatore Chirumbolo

Affiliations

Soon will be listed here.

Abstract

Since the increasing update of the biomolecular scientific literature, biomarkers in stroke have reached an outstanding and remarkable revision in the very recent years. Besides the diagnostic and prognostic role of some inflammatory markers, many further molecules and biological factors have been added to the list, including tissue derived cytokines, growth factor-like molecules, hormones, and microRNAs. The literatures on brain derived growth factor and other neuroimmune mediators, bone-skeletal muscle biomarkers, cellular and immunity biomarkers, and the role of microRNAs in stroke recovery were reviewed. To date, biomarkers represent a possible challenge in the diagnostic and prognostic evaluation of stroke onset, pathogenesis, and recovery. Many molecules are still under investigation and may become promising and encouraging biomarkers. Experimental and clinical research should increase this list and promote new discoveries in this field, to improve stroke diagnosis and treatment.

Citing Articles

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