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[Electrical Isolation of the Left Atrial Appendage : Benefits and Risks]

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Journal Herz
Date 2017 Mar 31
PMID 28357448
Citations 1
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Abstract

The left atrial appendage (LAA) is an extension originating from the body of the left atrium. The LAA is derived from the primary atrium and shows anatomical and physiological deviations from the left atrium. Different LAA morphologies exist. The LAA is not only the most frequent origin of intracardiac thrombi, it also frequently shows triggers responsible for the initiation or maintenance of atrial tachyarrhythmia and atrial fibrillation (AF). Isolation of the LAA using radiofrequency energy in addition to isolation of the pulmonary vein has recently gained importance due to the potential for increasing the clinical success rates, particularly in patients with persistent and long-standing persistent AF; however, after LAA isolation the incidence of LAA thrombi and systemic thromboembolisms might be increased even under treatment with oral anticoagulants, depending on the ablation strategy used. Thus, mechanical occlusion of the LAA should be discussed with patients after electrical isolation of the LAA.

Citing Articles

Two-dimensional versus three-dimensional transesophageal echocardiography in percutaneous left atrial appendage occlusion.

Streb W, Mitrega K, Podolecki T, Szymala M, Leopold-Jadczyk A, Kukulski T Cardiol J. 2018; 26(6):687-695.

PMID: 29512094 PMC: 8083037. DOI: 10.5603/CJ.a2018.0019.

References
1.
Bartus K, Morelli R, Szczepanski W, Kapelak B, Sadowski J, Lee R . Anatomic analysis of the left atrial appendage after closure with the LARIAT device. Circ Arrhythm Electrophysiol. 2014; 7(4):764-7. DOI: 10.1161/CIRCEP.113.001084. View

2.
Rillig A, Lin T, Schmidt B, Feige B, Heeger C, Wegner J . Experience matters: long-term results of pulmonary vein isolation using a robotic navigation system for the treatment of paroxysmal atrial fibrillation. Clin Res Cardiol. 2015; 105(2):106-16. DOI: 10.1007/s00392-015-0892-6. View

3.
Hocini M, Shah A, Nault I, Sanders P, Wright M, Narayan S . Localized reentry within the left atrial appendage: arrhythmogenic role in patients undergoing ablation of persistent atrial fibrillation. Heart Rhythm. 2011; 8(12):1853-61. PMC: 3393101. DOI: 10.1016/j.hrthm.2011.07.013. View

4.
Walker D, Phillips K . Left atrial catheter ablation subsequent to Watchman® left atrial appendage device implantation: a single centre experience. Europace. 2015; 17(9):1402-6. DOI: 10.1093/europace/euv037. View

5.
Whitlock R, Healey J, Vincent J, Brady K, Teoh K, Royse A . Rationale and design of the Left Atrial Appendage Occlusion Study (LAAOS) III. Ann Cardiothorac Surg. 2014; 3(1):45-54. PMC: 3904329. DOI: 10.3978/j.issn.2225-319X.2013.12.06. View