Prevalence of Valvular Heart Diseases and Associated Risk Factors in Han, Uygur and Kazak Population in Xinjiang, China

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2017 Mar 30

PMID 28355290

Citations 9

Authors

Yong-Tao Wang

Jing Tao

Ailifeire Maimaiti

Dilare Adi

Yi-Ning Yang

Xiao-Mei Li

Xiang Ma

Fen Liu

Bang-Dang Chen

Yi-Tong Ma

Affiliations

Soon will be listed here.

Abstract

Background: Valvular heart diseases (VHD) is very common in clinical practice and has became the subject of growing attention in the field of cardiovascular medicine. Our aim was to assess the prevalence and correlates of VHD in the general population in Xinjiang, China.

Methods: Using a 4-stage stratified cluster random sampling method, a total of 14618 participants were recruited in the Cardiovascular Risk Survey (CRS) study. The participants' personal information, medical history were assessed by questionnaire. VHD was diagnosed by transthoracic echocardiography. We carried out the statistical analysis utilizing SPSS Statistics version 19.0.

Results: In the total study group, VHD was observed in 1397 (9.65%) individuals. The prevalence rates of VHD in Han, Uygur and Kazak group are 13.51%, 2.71% and 12.29% respectively. The prevalence rates of VHD increased strikingly with age (all P < 0.001). The results of multinomial regression analysis indicated that VHD were related to age in Han group, to age smoking and hypertension in Uygur group, to age and hypertension in Kazak group.

Conclusion: Our research provides a unique prevalence rate of VHD in Xinjiang natural population. The result suggests that VHD are notably common in this population (9.65%) and increase with age. There exists significant difference of prevalence rate between ethnics. The main risk factors of VHD are age, hypertension and smoking. Valvular heart diseases should be regarded as a serious and growing public-health problem.

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