Clinical and Biological Features of Interval Colorectal Cancer

Overview

Journal Clin Endosc

Date 2017 Mar 22

PMID 28320200

Citations 13

Authors

Yu Mi Lee

Kyu Chan Huh

Affiliations

Soon will be listed here.

Abstract

Interval colorectal cancer (I-CRC) is defined as a CRC diagnosed within 60 months after a negative colonoscopy, taking into account that 5 years is the "mean sojourn time." It is important to prevent the development of interval cancer. The development of interval colon cancer is associated with female sex, old age, family history of CRC, comorbidities, diverticulosis, and the skill of the endoscopist. During carcinogenesis, sessile serrated adenomas/polyps (SSA/Ps) share many genomic and colonic site characteristics with I-CRCs. The clinical and biological features of I-CRC should be elucidated to prevent the development of interval colon cancer.

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