A Proposal for Standardized Grading of Chronic Changes in Native Kidney Biopsy Specimens

Overview

Journal Kidney Int

Publisher Elsevier

Specialty Nephrology

Date 2017 Mar 19

PMID 28314581

Citations 100

Authors

Sanjeev Sethi

Vivette D DAgati

Cynthia C Nast

Agnes B Fogo

An S De Vriese

Glen S Markowitz

Richard J Glassock

Fernando C Fervenza

Surya V Seshan

Andrew Rule

Lorraine C Racusen

Jai Radhakrishnan

Christopher G Winearls

Gerald B Appel

Ingeborg M Bajema

Anthony Chang

Robert B Colvin

H Terence Cook

Sundaram Hariharan

Loren P Herrera Hernandez

Neeraja Kambham

Michael Mengel

Karl A Nath

Helmut G Rennke

Pierre Ronco

Brad H Rovin

Mark Haas

Affiliations

Soon will be listed here.

Abstract

Chronic changes represent an important component of native kidney biopsy evaluation and have a major bearing on predicting prognosis and guiding treatment. We propose here a uniform, semiquantitative approach to assessing such changes, which include glomerulosclerosis, tubular atrophy, interstitial fibrosis, and arteriosclerosis, and we report these findings as an overall chronicity grade.

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