Enhancement of Synaptic Potentials in Rabbit CA1 Pyramidal Neurons Following Classical Conditioning

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1988 Mar 1

PMID 2830626

Citations 15

Authors

J L LoTurco

D A Coulter

D L Alkon

Affiliations

Soon will be listed here.

Abstract

A synaptic potential elicited by high-frequency stimulation of the Schaffer collaterals was enhanced in hippocampal CA1 pyramidal cells from rabbits that were classically conditioned relative to cells from control rabbits. In addition, confirming previous reports, the after-hyperpolarization was reduced in cells from conditioned animals. We suggest that reduced after-hyperpolarization and enhanced synaptic responsiveness in cells from conditioned animals work in concert to contribute to the functioning of hippocampal CA1 pyramidal cells during classical conditioning.

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