Sporulation Delay by Stable CAMP Analogues in the Slime MoldPhysarum Polycephalum

Overview

Journal Rouxs Arch Dev Biol

Specialty Biology

Date 2017 Mar 18

PMID 28306014

Authors

Christine Brandt

Bernd Jastorff

Armin Hildebrandt

Affiliations

Soon will be listed here.

Abstract

Plasmodial cells of the slime moldPhysarum polycephalum become competent for sporulation following a prolonged period of starvation in darkness. Then sporulation can be induced by illumination. Microinjections of the stable (Sp)- and (Rp)-diastereoisomers of adenosine cyclic 3',5' monothionophosphate before and during a sensitive period from the start of illumination until 5 h after lead to a significant delay in the sporulation process.Both of the diastereoisomers of cyclic AMP prolong the time for sporangia to form in darkness. However, the (Sp)-diastereoisomer is more effective and causes morphological changes in plasmodia.The experimental data suggest that cyclic AMP is decisively involved in light-induced differentiation in the lower eukaryotoPhysarum polycephalum.

References

Osborn M, Weber K . Actin paracrystal induction by forskolin and by db-cAMP in CHO cells. Exp Cell Res. 1984; 150(2):408-18. DOI: 10.1016/0014-4827(84)90584-6. View

Murray A, Spiszman M, Atkinson D . Adenosine 3',5'-monophosphate phosphodiesterase in the growth medium of Physarum polycephalum. Science. 1971; 171(3970):496-8. DOI: 10.1126/science.171.3970.496. View

Smith D, MANSOUR T . An adenosine-3',5'-monophosphate activated adenylate cyclase in the slime mold physarum polycephalum. FEBS Lett. 1978; 92(1):57-62. DOI: 10.1016/0014-5793(78)80721-2. View

Kuehn G . An adenosine 3',5'-monophosphate-inhibited protein kinase from Physarum polycephalum. J Biol Chem. 1971; 246(20):6366-9. View

Daniel J, Oleinick N, Whistler S . Choleragen-induced cyclic nucleotide response in a lower eukaryote. FEBS Lett. 1980; 122(1):138-42. DOI: 10.1016/0014-5793(80)80421-2. View

Daniel J, Rusch H . Niacin requirement for sporulation of Physarum polycephalum. J Bacteriol. 1962; 83:1244-50. PMC: 279441. DOI: 10.1128/jb.83.6.1244-1250.1962. View

Scholubbers H, Van Knippenberg P, Baraniak J, Stec W, Morr M, Jastorff B . Investigations on stimulation of lac transcription in vivo in Escherichia coli by cAMP analogues. Biological activities and structure-activity correlations. Eur J Biochem. 1984; 138(1):101-9. DOI: 10.1111/j.1432-1033.1984.tb07887.x. View

de Wit R, Hoppe J, Stec W, Baraniak J, Jastorff B . Interaction of cAMP derivatives with the 'stable' cAMP-binding site in the cAMP-dependent protein kinase type I. Eur J Biochem. 1982; 122(1):95-9. DOI: 10.1111/j.1432-1033.1982.tb05852.x. View

Jastorff B, Hoppe J, Morr M . A model for the chemical interactions of adenosine 3':5'-monophosphate with the R subunit of protein kinase type I. Refinement of the cyclic phosphate binding moiety of protein kinase type I. Eur J Biochem. 1979; 101(2):555-61. DOI: 10.1111/j.1432-1033.1979.tb19750.x. View

10.

van Haastert P, Jastorff B, Pinas J, Konijn T . Analogs of cyclic AMP as chemoattractants and inhibitors of Dictyostelium chemotaxis. J Bacteriol. 1982; 149(1):99-105. PMC: 216596. DOI: 10.1128/jb.149.1.99-105.1982. View

11.

Kupetz I, Jeter Jr J . Cell-cycle-specific activity of cyclic nucleotide phosphodiesterase in Physarum polycephalum. Cell Tissue Kinet. 1985; 18(2):159-68. DOI: 10.1111/j.1365-2184.1985.tb00645.x. View

12.

Kincaid R, MANSOUR T . Cyclic 3',5'AMP phosphodiesterase in Physarum polycephalum. II. Kinetic properties. Biochim Biophys Acta. 1979; 588(3):342-50. DOI: 10.1016/0304-4165(79)90342-8. View

13.

Garrison P, Barnes L . Cyclic AMP in the cell cycle of Physarum polycephalum. Biochim Biophys Acta. 1980; 633(1):114-21. DOI: 10.1016/0304-4165(80)90043-4. View

14.

Lovely J, Threlfall R . Adenylate cyclase and cyclic AMP phosphodiesterase activity during the mitotic cycle of Physarum polycephalum. Biochem Biophys Res Commun. 1978; 85(2):579-84. DOI: 10.1016/0006-291x(78)91202-0. View

15.

Walton G, Spiess J, Gill G . Phosphorylation of high mobility group 14 protein by cyclic nucleotide-dependent protein kinases. J Biol Chem. 1982; 257(8):4661-8. View

16.

Putzer H, Verfuerth C, Claviez M, Schreckenbach T . Photomorphogenesis in Physarum: induction of tubulins and sporulation-specific proteins and of their mRNAs. Proc Natl Acad Sci U S A. 1984; 81(22):7117-21. PMC: 392088. DOI: 10.1073/pnas.81.22.7117. View

17.

Jarvest R, Lowe G, Baraniak J, Stec W . A stereochemical investigation of the hydrolysis of cyclic AMP and the (Sp)-and (Rp)-diastereoisomers of adenosine cyclic 3':5'-phosphorothioate by bovine heart and baker's-yeast cyclic AMP phosphodiesterases. Biochem J. 1982; 203(2):461-70. PMC: 1158251. DOI: 10.1042/bj2030461. View

18.

Daniel J, Rusch H . The pure culture of Physarum polycephalum on a partially defined soluble medium. J Gen Microbiol. 1961; 25:47-59. DOI: 10.1099/00221287-25-1-47. View

19.

Ernest M . Induction of tyrosine aminotransferase mRNA by glucocorticoids and cAMP in fetal rat liver. Proc Natl Acad Sci U S A. 1982; 79(2):365-8. PMC: 345735. DOI: 10.1073/pnas.79.2.365. View

20.

de Wit R, Hekstra D, Jastorff B, Stec W, Baraniak J, VAN Driel R . Inhibitory action of certain cyclophosphate derivatives of cAMP on cAMP-dependent protein kinases. Eur J Biochem. 1984; 142(2):255-60. DOI: 10.1111/j.1432-1033.1984.tb08279.x. View