Granulocyte Transfusions in the Management of Invasive Fungal Infections

Overview

Journal Br J Haematol

Specialty Hematology

Date 2017 Mar 16

PMID 28295178

Citations 15

Authors

Kamille A West

Juan Gea-Banacloche

David Stroncek

Sameer S Kadri

Affiliations

Soon will be listed here.

Abstract

Granulocyte transfusions have a long history of being used in patients with neutropenia or neutrophil dysfunction to prevent and treat invasive fungal infections. However, there are limited and conflicting data concerning its clinical effectiveness, considerable variations in current granulocyte transfusion practices, and uncertainties about its benefit as an adjunct to modern antifungal therapy. In this review, we provide an overview on granulocyte transfusions and summarize the evidence on their role in the prevention and treatment of invasive fungal infections.

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