Effect of United States Buckwheat Honey on Antibiotic-resistant Hospital Acquired Pathogens

Overview

Journal Pan Afr Med J

Date 2017 Mar 16

PMID 28292167

Citations 4

Authors

Eric Nee-Armah Hammond

Megan Duster

Jackson Ssentalo Musuuza

Nasia Safdar

Affiliations

Soon will be listed here.

Abstract

Introduction: Due to an upsurge in antibiotic-resistant infections and lack of therapeutic options, new approaches are needed for treatment. Honey may be one such potential therapeutic option. We investigated the susceptibility of hospital acquired pathogens to four honeys from Wisconsin, United States, and then determined if the antibacterial effect of each honey against these pathogens is primarily due to the high sugar content.

Methods: Thirteen pathogens including: four , two Methicillin-resistant , two , one Methicillin-Susceptible , two Vancomycin-resistance Enterococcus, one and one were exposed to 1-50% (w/v) four Wisconsin honeys and Artificial honey to determine their minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) using the broth dilution method.

Results: Buckwheat honey predominantly exhibited a bactericidal mode of action against the tested pathogens, and this varied with each pathogen. isolates were more sensitive to the Wisconsin buckwheat honey as compared to the other pathogens. Artificial honey at 50% (w/v) failed to kill any of the pathogens. The high sugar content of Wisconsin buckwheat honey is not the only factor responsible for its bactericidal activity.

Conclusion: Wisconsin buckwheat honey has the potential to be an important addition to therapeutic armamentarium against resistant pathogens and should be investigated further.

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