Association of Rigid-Compulsive Behavior with Functional Constipation in Autism Spectrum Disorder

Overview

Journal J Autism Dev Disord

Publisher Springer

Date 2017 Mar 15

PMID 28289979

Citations 36

Authors

Sarah Marler

Bradley J Ferguson

Evon Batey Lee

Brittany Peters

Kent C Williams

Erin McDonnell

Eric A Macklin

Pat Levitt

Kara Gross Margolis

David Q Beversdorf

Jeremy Veenstra-VanderWeele

Affiliations

Soon will be listed here.

Abstract

Based upon checklist data from the Autism Speaks Autism Treatment Network, we hypothesized that functional constipation (FC) would be associated with rigid-compulsive behavior in children with autism spectrum disorder (ASD). We used the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III to assess FC symptoms in 108 children with ASD. As hypothesized, FC was associated with parent ratings on the Repetitive Behavior Scales-Revised (RBS-R) Compulsive, Ritualistic, and Sameness subscales in the overall population. Of note, FC was less common in children who were not taking medications that target behavior or treat FC. In the medication-free children, rigid-compulsive behavior was not significantly associated with FC. More research is needed to understand the mechanisms underlying these associations.

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