Clinical Features and Inflammatory Markers in Pediatric Pneumonia: a Prospective Study

Overview

Journal Eur J Pediatr

Specialty Pediatrics

Date 2017 Mar 11

PMID 28281094

Citations 18

Authors

Are Stuwitz Berg

Christopher Stephen Inchley

Hans Olav Fjaerli

Truls Michael Leegaard

Morten Lindbaek

Britt Nakstad

Affiliations

Soon will be listed here.

Abstract

Conclusion: With relatively high specificity and likelihood ratio CRP, WBC count and hypoxemia may be beneficial in ruling in a positive chest radiograph in suspected pneumonia and bacterial etiology in proven pneumonia, but with low sensitivity, the clinical utility is limited. What is Known: • Pneumonia is recommended to be a clinical diagnosis, and neither clinical features nor inflammatory markers can reliably distinguish etiology. • The etiology of pneumonia has changed after routine pneumococcal conjugate vaccine. What is New: • High CRP and WBC counts were associated with infiltrates in children with suspected pneumonia and with bacterial infection in proven pneumonia. • In the post-pneumococcal vaccination era, viral etiology is expected, and in cases of pneumonia with low CRP and WBC counts, a watch-and-wait strategy for antibiotic treatment may be applied.

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