» Articles » PMID: 28267895

Characteristics of Symptomatic Men with Testicular Microlithiasis - A Danish Cross-sectional Questionnaire Study

Overview
Journal Andrology
Date 2017 Mar 8
PMID 28267895
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

Testicular microlithiasis (TML) is an incidental finding at ultrasonography of the scrotum. A link between testicular microlithiasis and testicular cancer has been suggested. However, the majority of studies are retrospective using ultrasonography with minor data on health status and life style characteristics. Our objective was to investigate if lifestyle and health are associated with TML. In 2014, we conducted a self-administered questionnaire survey including 1538 men, who all due to testicular/scrotal symptoms had an ultrasound investigation of the scrotum during 2004-2013. The men were divided into men with TML and men without. The 23-items questionnaire included items on age, height, weight, lifestyle (alcohol consumptions, smoking habits, workload, exercise and food), previous diseases in the testicles, pain and consumption of analgesics. The prevalence of TML was 12.8%. Overall, lifestyle factors did not vary between men with or without TML. However, men with TML did consume more crisp than men without. Development of TML was not associated to classic life style factors such as alcohol consumption, smoking habits, or mothers smoking during pregnancy. Also, age and height could not be linked to presence of TML. We did find, however, that men with TML experienced less physical activity and consumed more crisp than men without TML. Since ingestion of crisps has potential carcinogenic effect (acrylamide), this finding needs confirmation in a separate study.

Citing Articles

An Insight into Testicular Macrocalcification-A Retrospective Study of 42 Cases on a Rare Sonographic Finding.

Pedersen M, Toft D, Lindebjerg J, Rafaelsen S, Lildal S Life (Basel). 2025; 15(2).

PMID: 40003615 PMC: 11857041. DOI: 10.3390/life15020205.


Testicular mass with macrocalcification and osseous metaplasia: A case report.

Pourjabali M, Noushyar M, Ghahramanpour A, Mansouri F SAGE Open Med Case Rep. 2024; 12:2050313X241266447.

PMID: 39161920 PMC: 11331461. DOI: 10.1177/2050313X241266447.


Association between risk factors and testicular microlithiasis.

Pedersen M, Moller H, Rafaelsen S, Moller J, Osther P, Vedsted P Acta Radiol Open. 2019; 8(9):2058460119870297.

PMID: 31588363 PMC: 6740053. DOI: 10.1177/2058460119870297.


Testicular microlithiasis: what urologists should know. A review of the current literature.

Balawender K, Orkisz S, Wisz P Cent European J Urol. 2018; 71(3):310-314.

PMID: 30386652 PMC: 6202617. DOI: 10.5173/ceju.2018.1728.


Testicular microlithiasis and testicular tumor: a review of the literature.

Leblanc L, Lagrange F, Lecoanet P, Marcon B, Eschwege P, Hubert J Basic Clin Androl. 2018; 28:8.

PMID: 30002831 PMC: 6036676. DOI: 10.1186/s12610-018-0073-3.

References
1.
McDonald M, Reed A, Tran P, Evans L . Testicular tumor ultrasound characteristics and association with histopathology. Urol Int. 2012; 89(2):196-202. DOI: 10.1159/000338771. View

2.
Kaijser M, Akre O, Cnattingius S, Ekbom A . Maternal lung cancer and testicular cancer risk in the offspring. Cancer Epidemiol Biomarkers Prev. 2003; 12(7):643-6. View

3.
Goede J, Hack W, van der Voort-Doedens L, Sijstermans K, Pierik F . Prevalence of testicular microlithiasis in asymptomatic males 0 to 19 years old. J Urol. 2009; 182(4):1516-20. DOI: 10.1016/j.juro.2009.06.065. View

4.
Johnson K, Gorzinski S, Bodner K, Campbell R, Wolf C, Friedman M . Chronic toxicity and oncogenicity study on acrylamide incorporated in the drinking water of Fischer 344 rats. Toxicol Appl Pharmacol. 1986; 85(2):154-68. DOI: 10.1016/0041-008x(86)90109-2. View

5.
Doherty F, Mullins T, Sant G, Drinkwater M, Ucci Jr A . Testicular microlithiasis. A unique sonographic appearance. J Ultrasound Med. 1987; 6(7):389-92. DOI: 10.7863/jum.1987.6.7.389. View