Imaging the Abdominal Manifestations of Cystic Fibrosis

Overview

Journal Int J Hepatol

Publisher Wiley

Specialty Gastroenterology

Date 2017 Mar 3

PMID 28250993

Citations 6

Authors

C D Gillespie

M K OReilly

G N Allen

S McDermott

V O Chan

C A Ridge

Affiliations

Soon will be listed here.

Abstract

Cystic fibrosis (CF) is a multisystem disease with a range of abdominal manifestations including those involving the liver, pancreas, and kidneys. Recent advances in management of the respiratory complications of the disease has led to a greater life expectancy in patients with CF. Subsequently, there is increasing focus on the impact of abdominal disease on quality of life and survival. Liver cirrhosis is the most important extrapulmonary cause of death in CF, yet significant challenges remain in the diagnosis of CF related liver disease. The capacity to predict those patients at risk of developing cirrhosis remains a significant challenge. We review representative abdominal imaging findings in patients with CF selected from the records of two academic health centres, with a view to increasing familiarity with the abdominal manifestations of the disease. We review their presentation and expected imaging findings, with a focus on the challenges facing diagnosis of the hepatic manifestations of the disease. An increased familiarity with these abdominal manifestations will facilitate timely diagnosis and management, which is paramount to further improving outcomes for patients with cystic fibrosis.

Citing Articles

Cystic fibrosis liver disease: A condition in need of structured transition and continuity of care.

Hercun J, Alvarez F, Vincent C, Bilodeau M Can Liver J. 2022; 2(3):71-83.

PMID: 35990223 PMC: 9202747. DOI: 10.3138/canlivj-2018-0019.

Surgical considerations in cystic fibrosis: what every general surgeon needs to know.

Chetwood J, Volovets A, Sivam S, Koh C ANZ J Surg. 2022; 92(10):2425-2432.

PMID: 35920692 PMC: 9804981. DOI: 10.1111/ans.17948.

Analysis of Clinical Manifestations, Imaging Features, and Gene Mutation Characteristics of 6 Children with Cystic Fibrosis in China.

Chu Y, Shuai J, Huang K, Liu J, Lv W, Li B Evid Based Complement Alternat Med. 2021; 2021:7254391.

PMID: 34765005 PMC: 8577894. DOI: 10.1155/2021/7254391.

Current Practices and Potential Nanotechnology Perspectives for Pain Related to Cystic Fibrosis.

Trandafir L, Leon M, Frasinariu O, Baciu G, Dodi G, Cojocaru E J Clin Med. 2019; 8(7).

PMID: 31336857 PMC: 6678759. DOI: 10.3390/jcm8071023.

Microgallbladder: Self-Remitting Acute Cholecystitis-Like Condition Unique to Patients with Cystic Fibrosis.

Mousa M, Feldman J, Mahajan P Case Rep Radiol. 2019; 2019:6737428.

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