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Secondary Metabolites from Polar Organisms

Overview
Journal Mar Drugs
Publisher MDPI
Specialties Biology
Pharmacology
Date 2017 Mar 1
PMID 28241505
Citations 35
Authors
Affiliations
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Abstract

Polar organisms have been found to develop unique defences against the extreme environment environment, leading to the biosynthesis of novel molecules with diverse bioactivities. This review covers the 219 novel natural products described since 2001, from the Arctic and the Antarctic microoganisms, lichen, moss and marine faunas. The structures of the new compounds and details of the source organism, along with any relevant biological activities are presented. Where reported, synthetic and biosynthetic studies on the polar metabolites have also been included.

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