[Spontaneous Remission of HCV Infection After Autologous Stem Cell Transplantation in a 58-year-old Man]

Overview

Journal Internist (Berl)

Specialty General Medicine

Date 2017 Feb 26

PMID 28235985

Authors

L Reinhardt

H Eiffert

G Wulf

P Strobel

S C B Bremer

A Amanzada

V Ellenrieder

A Neesse

Affiliations

Soon will be listed here.

Abstract

We report about a 58-year-old man with a chronic and treatment-naive hepatitis C virus (HCV) infection of genotype 1b, who had undergone autologous stem cell transplantation twice due to multiple myeloma. Subsequently, a high-level viremic reactivation of an occult hepatitis B virus (HBV) infection and also a reverse seroconversion was observed. Furthermore, a sustained spontaneous remission of HCV infection was seen. Antiviral therapy of HBV infection was initiated with tenofovir. Seven months after therapy initiation, the patient acquired an "anti-HBc-only" status. Antiviral therapy with tenofovir is still continued. The patient is in a good clinical condition.

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