Assessment of Human Dietary Exposure to Arsenic Through Rice

Overview

Journal Sci Total Environ

Date 2017 Feb 25

PMID 28233618

Citations 36

Authors

Matthew A Davis

Antonio J Signes-Pastor

Maria Argos

Francis Slaughter

Claire Pendergrast

Tracy Punshon

Anala Gossai

Habibul Ahsan

Margaret R Karagas

Affiliations

Soon will be listed here.

Abstract

Rice accumulates 10-fold higher inorganic arsenic (i-As), an established human carcinogen, than other grains. This review summarizes epidemiologic studies that examined the association between rice consumption and biomarkers of arsenic exposure. After reviewing the literature we identified 20 studies, among them included 18 observational and 2 human experimental studies that reported on associations between rice consumption and an arsenic biomarker. Among individuals not exposed to contaminated water, rice is a source of i-As exposure - rice consumption has been consistently related to arsenic biomarkers, and the relationship has been clearly demonstrated in experimental studies. Early-life i-As exposure is of particular concern due to its association with lifelong adverse health outcomes. Maternal rice consumption during pregnancy also has been associated with infant toenail total arsenic concentrations indicating that dietary exposure during pregnancy results in fetal exposure. Thus, the collective evidence indicates that rice is an independent source of arsenic exposure in populations around the world and highlights the importance of investigating its affect on health.

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