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Nuclear Protein(s) Binding to the Conserved DNA Hexameric Sequence Postulated to Regulate Transcription of Wheat Histone Genes

Overview
Journal FEBS Lett
Specialty Biochemistry
Date 1987 Nov 2
PMID 2822486
Citations 34
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Abstract

Nuclear protein(s) that specifically bind(s) to the upstream hexamer motif, ACGTCA, of wheat histone H3 and H4 genes has (have) been identified. Sequences homologous to this hexamer are found to be conserved in the upstream region of not only wheat histone genes but also other plant and animal histone genes. This suggests a possible role(s) for the hexamer and the nuclear protein(s) in the transcriptional regulation of the wheat histone genes. This hexamer is homologous to the upstream core sequence, TGACGTCA, which is highly conserved in some animal genes whose expression is regulated by cAMP.

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