» Articles » PMID: 28217650

Comparing the Effect of Dressing Versus No-dressing on Exit Site Infection and Peritonitis in Chronic Ambulatory Peritoneal Dialysis Patients

Overview
Journal Adv Biomed Res
Date 2017 Feb 21
PMID 28217650
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

Bachground: Peritonitis and exit site (ES) infection are two main complications of peritoneal dialysis. There are some controversies regard to preventive strategies for ES care. In this study we compared peritonitis and ES infection rates in patients with and without dressing.

Materials And Methods: This historical cohort study carried out on 72 patients under continuous ambulatory peritoneal dialysis treatment, 54 with dressing versus 18 patients without dressing, followed from October 1, 2010 to March 31, 2011 for peritonitis and ES infection.

Results: A total of 17 episodes of ES infection occurred in 12 patients in dressing group, but no case was seen in no-dressing group ( = 0.02). Twenty-one episodes of peritonitis occurred in 15 patients in both groups (one episode every 20.6 patient-months). In no-dressing group two episodes occurred in only one patient (one episode every 54 patient-months), and in dressing group, 19 episode in 14 patients (one episode every 17.1 patient-months) ( = 0.03). Peritonitis was significantly more frequent in male versus female in overall patients (38% vs. 14%, = 0.025) and in dressing group (52% vs. 15%, = 0.003). In dressing group, peritonitis was more frequent in diabetics versus non-diabetics (48% vs. 11%, = 0.01). Odds ratio for developing peritonitis was 9.4 in dressing group (95% confidence interval [CI] =1.05 - 84.4; = 0.045), and 4.4 in men (95% CI = 1.26 - 15.19; = 0.02).

Conclusion: In this study, chronic ES care without dressing was associated with lower risk of peritonitis and ES infection.

Citing Articles

An outbreak of complex exit site infection among peritoneal dialysis patients caused by contaminated spray dressing.

Cheng L, Chau S, Chan W, Chen J, Wong B, Fung K Infect Prev Pract. 2024; 6(2):100359.

PMID: 38559368 PMC: 10981104. DOI: 10.1016/j.infpip.2024.100359.


Catheter-related infections in peritoneal dialysis: comparison of a single center results and the literature data.

Milan Manani S, Virzi G, Giuliani A, Crepaldi C, Ronco C J Nephrol. 2019; 32(5):837-841.

PMID: 30955154 DOI: 10.1007/s40620-019-00604-3.

References
1.
Danguilan R, Evangelista L, Abrenica M, Rondilla S . Comparative study of mupirocin and sodium fucidate in the prophylaxis of exit-site infections in CAPD patients. Perit Dial Int. 2004; 23(6):593-5. View

2.
Conly J, Vas S . Increasing mupirocin resistance of Staphylococcus aureus in CAPD--should it continue to be used as prophylaxis?. Perit Dial Int. 2003; 22(6):649-52. View

3.
Piraino B, Bernardini J, Bender F . An analysis of methods to prevent peritoneal dialysis catheter infections. Perit Dial Int. 2008; 28(5):437-43. View

4.
Piraino B, Bernardini J, Sorkin M . Catheter infections as a factor in the transfer of continuous ambulatory peritoneal dialysis patients to hemodialysis. Am J Kidney Dis. 1989; 13(5):365-9. DOI: 10.1016/s0272-6386(89)80018-6. View

5.
Bayston R, Andrews M, Rigg K, Shelton A . Recurrent infection and catheter loss in patients on continuous ambulatory peritoneal dialysis. Perit Dial Int. 2000; 19(6):550-5. View