Association of Serum Leptin with Serum C-reactive Protein in Hemodialysis Patients

Overview

Journal J Nephropharmacol

Specialty Pharmacology

Date 2017 Feb 16

PMID 28197429

Citations 4

Authors

Ebrahim Rastegari

Hamid Nasri

Affiliations

Soon will be listed here.

Abstract

Recent investigations have shown that leptin is cleared principally by the kidney. To examine whether and how in patients on hemodialysis the level of C-reactive protein level correlate with serum leptin. The total patients were 36. The mean patients' age were 46 (16) years. The median length of the time patients were on hemodialysis were 19 months. The mean serum C-reactive protein was 8.7 (6.6) mg/l (median: 8 mg/l). The mean serum leptin was 9.4 (14) ng/ml (median: 5.75 ng/ml). In this study we found a significant inverse correlation of serum leptin with serum C-reactive protein (r= -0.57, p= 0.041) was seen. Our data supports, the positive effect of leptin on nutrition and support the theory of protective effects (reverse epidemiology) of leptin in hemodialysis patients.

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