F-FDG-PET/CT Angiography for the Diagnosis of Infective Endocarditis

Overview

Journal Curr Cardiol Rep

Publisher Current Science

Specialty Cardiology & Vascular Diseases

Date 2017 Feb 11

PMID 28185172

Citations 7

Authors

A Roque

M N Pizzi

H Cuellar-Calabria

S Aguade-Bruix

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: This article reviews the current imaging role of F-fluordeoxyglucose positron emission computed tomography (F-FDG-PET/CT) combined with cardiac CT angiography (CTA) in infective endocarditis and discusses the strengths and limitations of this technique.

Recent Findings: The diagnosis of infective endocarditis affecting prosthetic valves and intracardiac devices is challenging because echocardiography and, therefore, the modified Duke criteria have well-recognized limitations in this clinical scenario. The high sensitivity of F-FDG-PET/CT for the detection of infection associated with the accurate definition of structural damage by gated cardiac CTA in a combined technique (PET/CTA) has provided a significant increase in diagnostic sensitivity for the detection of IE. PET/CTA has proven to be a useful diagnostic tool in patients with suspected infective endocarditis. The additional information provided by this technique improves diagnostic performance in prosthetic valve endocarditis when it is used in combination with the Duke criteria. The findings obtained in PET/CTA studies have been included as a major criterion in the recently updated diagnostic algorithm in infective endocarditis guidelines.

Citing Articles

The valve uptake index: improving assessment of prosthetic valve endocarditis and updating [18F]FDG PET/CT(A) imaging criteria.

Roque A, Pizzi M, Fernandez-Hidalgo N, Romero-Farina G, Burcet G, Reyes-Juarez J Eur Heart J Cardiovasc Imaging. 2022; 23(9):1260-1271.

PMID: 34999818 PMC: 9365301. DOI: 10.1093/ehjci/jeab279.

Case Report: F-FDG PET-CT for Diagnosing Prosthetic Device-Related Infection in an Infant With CHD.

Kawamura J, Ueno K, Taimura E, Matsuba T, Imoto Y, Jinguji M Front Pediatr. 2021; 9:584741.

PMID: 33763393 PMC: 7982821. DOI: 10.3389/fped.2021.584741.

Procedural recommendations of cardiac PET/CT imaging: standardization in inflammatory-, infective-, infiltrative-, and innervation (4Is)-related cardiovascular diseases: a joint collaboration of the EACVI and the EANM.

Slart R, Glaudemans A, Gheysens O, Lubberink M, Kero T, Dweck M Eur J Nucl Med Mol Imaging. 2020; 48(4):1016-1039.

PMID: 33106926 PMC: 8041672. DOI: 10.1007/s00259-020-05066-5.

Multimodality Imaging in the Diagnostic Work-Up of Endocarditis and Cardiac Implantable Electronic Device (CIED) Infection.

Galea N, Bandera F, Lauri C, Autore C, Laghi A, Erba P J Clin Med. 2020; 9(7).

PMID: 32674517 PMC: 7408824. DOI: 10.3390/jcm9072237.

Diagnostic challenges in infective endocarditis: is PET/CT the solution?.

Hohmann C, Michels G, Schmidt M, Pfister R, Mader N, Ohler M Infection. 2019; 47(4):579-587.

PMID: 30847769 DOI: 10.1007/s15010-019-01278-6.

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