A Complicated Multisystem Flare of Systemic Lupus Erythematosus During Pregnancy

Overview

Journal BMJ Case Rep

Specialty General Medicine

Date 2017 Feb 10

PMID 28179384

Citations 1

Authors

Philip Webster

Catherine Nelson-Piercy

Liz Lightstone

Affiliations

Soon will be listed here.

Abstract

We report a case of systemic lupus erythematosus (SLE) in a young woman who became pregnant amid a severe flare. She continued to have active disease in the face of aggressive treatments complicated by several side effects of immunosuppressive drugs including recurrent sepsis and gestational diabetes. Her fetus was at risk for congenital heart block during the second and third trimesters. Despite an extremely guarded prognosis, she delivered a healthy baby girl. This case highlights the complexities of SLE management during pregnancy. We discuss the therapeutic options available in pregnancy, and highlight the importance of cross-specialty multidisciplinary care in these women.

Citing Articles

Clinical practice guideline on pregnancy and renal disease.

Wiles K, Chappell L, Clark K, Elman L, Hall M, Lightstone L BMC Nephrol. 2019; 20(1):401.

PMID: 31672135 PMC: 6822421. DOI: 10.1186/s12882-019-1560-2.

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