Tuning Cell Adhesive Properties Via Layer-by-layer Assembly of Chitosan and Alginate

Overview

Journal Acta Biomater

Publisher Elsevier

Specialty Biomedical Engineering

Date 2017 Jan 28

PMID 28126597

Citations 16

Authors

Joana M Silva

Jose R Garcia

Rui L Reis

Andres J Garcia

Joao F Mano

Affiliations

Soon will be listed here.

Abstract

Statement Of Significance: Multilayered films based on marine-derived polysaccharides were obtained by layer-by-layer (LbL). Biological tests with human umbilical vein endothelial cells (HUVECs) showed the potential of these films to tailor cell adhesion, spreading and proliferation. These multilayered films promise to be versatile and tunable model of cell adhesive and non-adhesive films.

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References

Wittmer C, Phelps J, Lepus C, Saltzman W, Harding M, Van Tassel P . Multilayer nanofilms as substrates for hepatocellular applications. Biomaterials. 2008; 29(30):4082-90. PMC: 2637394. DOI: 10.1016/j.biomaterials.2008.06.027. View

Cui L, Jia J, Guo Y, Liu Y, Zhu P . Preparation and characterization of IPN hydrogels composed of chitosan and gelatin cross-linked by genipin. Carbohydr Polym. 2013; 99:31-8. DOI: 10.1016/j.carbpol.2013.08.048. View

Silva J, Duarte A, Caridade S, Picart C, Reis R, Mano J . Tailored freestanding multilayered membranes based on chitosan and alginate. Biomacromolecules. 2014; 15(10):3817-26. PMC: 5097862. DOI: 10.1021/bm501156v. View

Lim F, Sun A . Microencapsulated islets as bioartificial endocrine pancreas. Science. 1980; 210(4472):908-10. DOI: 10.1126/science.6776628. View

Wittmer C, Phelps J, Saltzman W, Van Tassel P . Fibronectin terminated multilayer films: protein adsorption and cell attachment studies. Biomaterials. 2006; 28(5):851-60. PMC: 1773012. DOI: 10.1016/j.biomaterials.2006.09.037. View

Costa R, Custodio C, Arias F, Rodriguez-Cabello J, Mano J . Layer-by-layer assembly of chitosan and recombinant biopolymers into biomimetic coatings with multiple stimuli-responsive properties. Small. 2011; 7(18):2640-9. DOI: 10.1002/smll.201100875. View

Boura C, Menu P, Payan E, Picart C, Voegel J, Muller S . Endothelial cells grown on thin polyelectrolyte mutlilayered films: an evaluation of a new versatile surface modification. Biomaterials. 2003; 24(20):3521-30. DOI: 10.1016/s0142-9612(03)00214-x. View

Silva J, Caridade S, Oliveira N, Reis R, Mano J . Chitosan-alginate multilayered films with gradients of physicochemical cues. J Mater Chem B. 2020; 3(22):4555-4568. DOI: 10.1039/c5tb00082c. View

Chen H, Ouyang W, Lawuyi B, Martoni C, Prakash S . Reaction of chitosan with genipin and its fluorogenic attributes for potential microcapsule membrane characterization. J Biomed Mater Res A. 2005; 75(4):917-27. DOI: 10.1002/jbm.a.30492. View

10.

Cascone M, Barbani N, Cristallini C, Giusti P, Ciardelli G, Lazzeri L . Bioartificial polymeric materials based on polysaccharides. J Biomater Sci Polym Ed. 2001; 12(3):267-81. DOI: 10.1163/156856201750180807. View

11.

Richert L, Lavalle P, Payan E, Shu X, Prestwich G, Stoltz J . Layer by layer buildup of polysaccharide films: physical chemistry and cellular adhesion aspects. Langmuir. 2005; 20(2):448-58. DOI: 10.1021/la035415n. View

12.

Engler A, Bacakova L, Newman C, Hategan A, Griffin M, Discher D . Substrate compliance versus ligand density in cell on gel responses. Biophys J. 2003; 86(1 Pt 1):617-28. PMC: 1303831. DOI: 10.1016/S0006-3495(04)74140-5. View

13.

Detzel C, Larkin A, Rajagopalan P . Polyelectrolyte multilayers in tissue engineering. Tissue Eng Part B Rev. 2011; 17(2):101-13. PMC: 3062467. DOI: 10.1089/ten.TEB.2010.0548. View

14.

Schneider A, Francius G, Obeid R, Schwinte P, Hemmerle J, Frisch B . Polyelectrolyte multilayers with a tunable Young's modulus: influence of film stiffness on cell adhesion. Langmuir. 2006; 22(3):1193-200. DOI: 10.1021/la0521802. View

15.

Borges J, Mano J . Molecular interactions driving the layer-by-layer assembly of multilayers. Chem Rev. 2014; 114(18):8883-942. DOI: 10.1021/cr400531v. View

16.

Larkin A, Davis R, Rajagopalan P . Biocompatible, detachable, and free-standing polyelectrolyte multilayer films. Biomacromolecules. 2010; 11(10):2788-96. DOI: 10.1021/bm100867h. View

17.

Weber N, Pesnell A, Bolikal D, Zeltinger J, Kohn J . Viscoelastic properties of fibrinogen adsorbed to the surface of biomaterials used in blood-contacting medical devices. Langmuir. 2007; 23(6):3298-304. DOI: 10.1021/la060500r. View

18.

Malafaya P, Silva G, Reis R . Natural-origin polymers as carriers and scaffolds for biomolecules and cell delivery in tissue engineering applications. Adv Drug Deliv Rev. 2007; 59(4-5):207-33. DOI: 10.1016/j.addr.2007.03.012. View

19.

Gao L, Gan H, Meng Z, Gu R, Wu Z, Zhang L . Effects of genipin cross-linking of chitosan hydrogels on cellular adhesion and viability. Colloids Surf B Biointerfaces. 2014; 117:398-405. DOI: 10.1016/j.colsurfb.2014.03.002. View

20.

Tryoen-Toth P, Vautier D, Haikel Y, Voegel J, Schaaf P, Chluba J . Viability, adhesion, and bone phenotype of osteoblast-like cells on polyelectrolyte multilayer films. J Biomed Mater Res. 2002; 60(4):657-67. DOI: 10.1002/jbm.10110. View