"On-off"-induced Lethal Hyperthermia

Overview

Journal Mov Disord

Date 1989 Jan 1

PMID 2811893

Citations 6

Authors

R F Pfeiffer

E L Sucha

Affiliations

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Abstract

Neuroleptic malignant syndrome (NMS) is being increasingly recognized as a potential complication of neuroleptic therapy. Similar hyperthermic episodes have also been described in other settings of abrupt cessation of dopaminergic stimulation such as levodopa withdrawal. We report a fatal NMS-like episode occurring as a complication of an "off" period in a patient with Parkinson's disease.

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