Hepatocellular Carcinoma in Identical Twins in Chile: Case Report
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Liver cancer is the second leading cause of cancer death worldwide, with hepatocellular carcinoma (HCC) being the most common type of primary malignant liver tumour, with a typically poor prognosis, growing incidence and a well-documented relationship with chronic inflammation factors of the liver tissue. Despite the fact that family medical history has been identified as a risk factor for the development of HCC, its significance in terms of etiopathogenesis and prognosis is not well documented. With a view to contributing to this discussion, we will report the clinical case of two identical twins with HCC, both diagnosed within a short period of time, by providing relevant clinical data, and relating this to other medical literature reports that could contribute to a deeper understanding of this illness.
Familial hepatocellular carcinoma: 'A model for studying preventive and therapeutic measures'.
Weledji E Ann Med Surg (Lond). 2018; 35:129-132.
PMID: 30305894 PMC: 6172566. DOI: 10.1016/j.amsu.2018.09.035.