Long-term Esophageal Motility Changes After Thyroidectomy: Associations with Aerodigestive Disorders

Overview

Journal G Chir

Specialty General Surgery

Date 2017 Jan 19

PMID 28098054

Citations 13

Authors

G Scerrino

A Inviati

S Di Giovanni

N C Paladino

V Di Paola

C Raspanti

G I Melfa

F Cupido

S Mazzola

C Porrello

S Bonventre

G Gullotta

Affiliations

Soon will be listed here.

Abstract

Background: Patients undergoing thyroidectomy often complain aerodigestive disorders. In a previous study we showed the associations between voice impairment and proximal acid reflux, swallowing impairment and Upper Esophageal Sphyncter (UES) incoordination and the decrease in UES pressure in thirty-six patients observed before and soon afterwards uncomplicated thyroidectomy. This study investigated the state of post-thyroidectomy esophageal motility changes and its associations with these disorders after 18-24 months.

Patients And Methods: The thirty-six patients prospectively recruited according to selection criteria (thyroid volume ≤60 ml, benign disease, age 18-65 years, previous neck surgery, thyroiditis, pre- or postoperative vocal cord palsy) underwent voice (VIS) and swallowing (SIS) impairment scores, esophageal manometry and pH monitoring once again.

Results: After 18-24 months, both VIS and SIS recovered (respectively: p=0,022; p=0,0001); UES pressure increased (p=0,0001) nearing the preoperative values. The persistence of swallowing complaints were associated with the persistence of esophageal incoordination (p=0,03); the association between voice impairment and proximal acid reflux was confirmed (p<0,001).

Conclusions: Our study confirms that aerodigestive disorders after uncomplicated thyroidectomy, largely transient, are strictly connected with upper esophageal motility changes. In this viewpoint, the innervation of upper aerodigestive anatomical structures (larynx, pharynx, upper esophagus) and its variations should be focused.

Citing Articles

Adhesion Reduction Agent Guardix-SG Versus MegaShield for Postoperative Swallowing Function Analysis in Thyroidectomy Patients.

Lee H, Hwang J, Jo S, Kim J, Lee C, Kang S Clin Med Insights Oncol. 2024; 18:11795549241271715.

PMID: 39507701 PMC: 11539078. DOI: 10.1177/11795549241271715.

Post-thyroidectomy voice and swallowing disorders and association with laryngopharyngeal reflux: A scoping review.

Rodriguez A, Hans S, Lechien J Laryngoscope Investig Otolaryngol. 2023; 8(1):140-149.

PMID: 36846433 PMC: 9948583. DOI: 10.1002/lio2.1009.

Effects of Intraoperative Nerve Monitoring Techniques on Voice and Swallowing Disorders after Uncomplicated Thyroidectomy: Preliminary Report of a Bi-Institutional Prospective Study.

Melfa G, Siragusa G, Cocorullo G, Guzzino M, Raspanti C, Albanese L J Clin Med. 2023; 12(1).

PMID: 36615105 PMC: 9821617. DOI: 10.3390/jcm12010305.

Weight Gain and Asthenia Following Thyroidectomy: Current Knowledge from Literature Review.

Scerrino G, Salamone G, Corigliano A, Richiusa P, Proclama M, Radellini S J Clin Med. 2022; 11(18).

PMID: 36143133 PMC: 9500853. DOI: 10.3390/jcm11185486.

Thyroidectomy-related Swallowing Difficulties: Review of the Literature.

danic-Hadzibegovic A, Hergesic F, Babic E, Slipac J, Prstacic R Acta Clin Croat. 2021; 59(Suppl 1):38-49.

PMID: 34219883 PMC: 8212616. DOI: 10.20471/acc.2020.59.s1.05.

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