Theoretical Implications of a Pre-Erythrocytic Plasmodium Vivax Vaccine for Preventing Relapses

Overview

Journal Trends Parasitol

Specialty Parasitology

Date 2017 Jan 13

PMID 28077251

Citations 23

Authors

Michael White

Rogerio Amino

Ivo Mueller

Affiliations

Soon will be listed here.

Abstract

Preventing malaria infection through vaccination requires preventing every sporozoite inoculated by mosquito bite: a major challenge for Plasmodium falciparum. Plasmodium vivax sporozoites consist of tachysporozoites causing primary infection and bradysporozoites leading to relapses. We hypothesise that a candidate P. vivax vaccine with low efficacy against primary infection may substantially reduce transmission by preventing relapses.

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