First Evidence of Angiostrongyliasis Caused by in Guadeloupe, Lesser Antilles

Overview

Journal Am J Trop Med Hyg

Specialty Tropical Medicine

Date 2017 Jan 11

PMID 28070007

Citations 13

Authors

Celine Dard

Jean-Eudes Piloquet

Yvonne Qvarnstrom

LeAnne M Fox

Helmi Mkada

Jean-Christophe Hebert

Didier Mattera

Dorothee Harrois

Affiliations

Soon will be listed here.

Abstract

Infection by the rat lungworm represents the most common cause of infectious eosinophilic meningitis in humans, causing central nervous system (CNS) angiostrongyliasis. Most of CNS angiostrongyliasis cases were described in Asia, Pacific Basin, Australia, and some limited parts of Africa and America. CNS angiostrongyliasis has been reported in the Caribbean but never in the Lesser Antilles. The primary objectives of this study were to depict the first case of CNS angiostrongyliasis in the Lesser Antilles and investigate the environmental presence of in Guadeloupe, Lesser Antilles. In December 2013, a suspected case of CNS angiostrongyliasis in an 8-month-old infant in Guadeloupe was investigated by real-time polymerase chain reaction (PCR) testing on cerebral spinal fluid (CSF). The environmental investigation was performed by collecting molluscs from different parts of Guadeloupe and testing the occurrence of by real-time PCR. CSF from the suspected case of angiostrongyliasis was positive for by real-time PCR. Among 34 collected snails for environmental investigation, 32.4% were positive for . In conclusion, we report the first laboratory-confirmed case of CNS-angiostrongyliasis in the Lesser Antilles. We identified the presence and high prevalence of in in Guadeloupe. These results highlight the need to increase awareness of this disease and implement public health programs in the region to prevent human cases of angiostrongyliasis and improve management of eosinophilic meningitis patients.

Citing Articles

Molecular study of the status of Angiostrongylus cantonensis in rats in Haiti.

Fedna J, Borne R, Rieffel D, Bornette G, Henrys J, Grenouillet F Parasite. 2025; 31:64.

PMID: 39853112 PMC: 11465708. DOI: 10.1051/parasite/2024063.

Snail coprophagy: the encounter filter, food preferences, and rat lungworm (Angiostrongylus cantonensis) prevalence.

Rollins R, Griffin C, Cowie R Parasite. 2024; 31:76.

PMID: 39715443 PMC: 11666226. DOI: 10.1051/parasite/2024075.

A Scoping Review of Angiostrongyliasis and Other Diseases Associated with Terrestrial Mollusks, Including : An Overview of Case Reports and Series.

Villanueva Parra I, Munoz Diaz V, Martinez Guevara D, Cruz Mosquera F, Prieto-Alvarado D, Liscano Y Pathogens. 2024; 13(10).

PMID: 39452733 PMC: 11510296. DOI: 10.3390/pathogens13100862.

Paratenic hosts of and their relation to human neuroangiostrongyliasis globally.

Turck H, Fox M, Cowie R One Health. 2022; 15:100426.

PMID: 36277113 PMC: 9582568. DOI: 10.1016/j.onehlt.2022.100426.

Clinical Efficacy and Safety of Albendazole and Other Benzimidazole Anthelmintics for Rat Lungworm Disease (Neuroangiostrongyliasis): A Systematic Analysis of Clinical Reports and Animal Studies.

Jacob J, Steel A, Lin Z, Berger F, Zoeller K, Jarvi S Clin Infect Dis. 2021; 74(7):1293-1302.

PMID: 34448480 PMC: 8994584. DOI: 10.1093/cid/ciab730.

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