Enzymatic Antioxidant System of Endotheliocytes

Overview

Journal Dokl Biochem Biophys

Specialties Biochemistry
Biophysics

Date 2017 Jan 7

PMID 28058676

Citations 7

Authors

M G Sharapov

R G Goncharov

A E Gordeeva

V I Novoselov

O A Antonova

A K Tikhaze

V Z Lankin

Affiliations

Soon will be listed here.

Abstract

It is shown that endothelial cells from human umbilical vein have a reduced activity and gene expression of the "classic" antioxidant enzymes (Cu,Zn-superoxide dismutase, catalase, and Se-containing glutathione peroxidase). At the same time, a high expression level of peroxiredoxin genes was identified in the same endothelial cells, which obviously indicates the predominant involvement of these enzymes in protecting the endothelium from the damaging effect of free radical peroxidation.

Citing Articles

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Influence of electromagnetic waves, with maxima in the green or red range, on the morphofunctional properties of multipotent stem cells.

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