Evidence and Evidence Gaps of Laryngeal Cancer Surgery

Overview

Journal GMS Curr Top Otorhinolaryngol Head Neck Surg

Date 2016 Dec 28

PMID 28025603

Citations 4

Authors

Susanne Wiegand

Affiliations

Soon will be listed here.

Abstract

Surgical treatment of laryngeal cancer has been established for decades. In addition to total laryngectomy, which was first performed in 1873, a large number or organ preservation surgical techniques, like open partial laryngectomy, transoral laser microsurgery, and transoral robotic surgery have been developed. Studies on laryngeal cancer surgery are mainly retrospective case series and cohort studies. The evolution of chemoradiation protocols and their analysis in prospective randomized trials have led to an increasing acceptance of non-surgical treatment procedures. In addition to an improvement of prognosis, in recent years the preservation of function and maintenance of life quality after primary therapy of laryngeal cancer has increasingly become the focus of therapy planning. Significant late toxicity after chemoradiation has been identified as an important issue. This leads to a reassessment of surgical concepts and initiation of studies on laryngeal cancer surgery which was additionally stimulated by the advent of transoral robotic surgery in the US. Improving the evidence base of laryngeal cancer surgery by successful establishment of surgical trials should be the future goal.

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References

Morrissey A, OConnell D, Garg S, Seikaly H, Harris J . Radial forearm versus anterolateral thigh free flaps for laryngopharyngectomy defects: prospective, randomized trial. J Otolaryngol Head Neck Surg. 2010; 39(4):448-53. View

Davis G, Schwartz S, Veenstra D, Yueh B . Cost comparison of surgery vs organ preservation for laryngeal cancer. Arch Otolaryngol Head Neck Surg. 2005; 131(1):21-6. DOI: 10.1001/archotol.131.1.21. View

Hanna E, Sherman A, Cash D, Adams D, Vural E, Fan C . Quality of life for patients following total laryngectomy vs chemoradiation for laryngeal preservation. Arch Otolaryngol Head Neck Surg. 2004; 130(7):875-9. DOI: 10.1001/archotol.130.7.875. View

Simo R, Bradley P, Chevalier D, Dikkers F, Eckel H, Matar N . European Laryngological Society: ELS recommendations for the follow-up of patients treated for laryngeal cancer. Eur Arch Otorhinolaryngol. 2014; 271(9):2469-79. DOI: 10.1007/s00405-014-2966-x. View

de Gier H, Knegt P, de Boer M, Meeuwis C, van der Velden L, Kerrebijn J . CO2-laser treatment of recurrent glottic carcinoma. Head Neck. 2001; 23(3):177-80. DOI: 10.1002/1097-0347(200103)23:3<177::aid-hed1015>3.0.co;2-8. View

Johnson J, Myers E, Thearle P, Sigler B, Schramm Jr V . Antimicrobial prophylaxis for contaminated head and neck surgery. Laryngoscope. 1984; 94(1):46-51. DOI: 10.1002/lary.5540940111. View

Pantazis D, Liapi G, Kostarelos D, Kyriazis G, Pantazis T, Riga M . Glottic and supraglottic pT3 squamous cell carcinoma: outcomes with transoral laser microsurgery. Eur Arch Otorhinolaryngol. 2015; 272(8):1983-90. DOI: 10.1007/s00405-015-3611-z. View

Liang J, Li Z, Li S, Fang F, Zhao Y, Li Y . Pharyngocutaneous fistula after total laryngectomy: A systematic review and meta-analysis of risk factors. Auris Nasus Larynx. 2015; 42(5):353-9. DOI: 10.1016/j.anl.2015.04.002. View

Singer S, Danker H, Guntinas-Lichius O, Oeken J, Pabst F, Schock J . Quality of life before and after total laryngectomy: results of a multicenter prospective cohort study. Head Neck. 2013; 36(3):359-68. DOI: 10.1002/hed.23305. View

10.

Lawson G, Mendelsohn A, Van der Vorst S, Bachy V, Remacle M . Transoral robotic surgery total laryngectomy. Laryngoscope. 2012; 123(1):193-6. DOI: 10.1002/lary.23287. View

11.

Mahler V, Boysen M, Brondbo K . Radiotherapy or CO(2) laser surgery as treatment of T(1a) glottic carcinoma?. Eur Arch Otorhinolaryngol. 2009; 267(5):743-50. DOI: 10.1007/s00405-009-1135-0. View

12.

Naudo P, Laccourreye O, Weinstein G, Jouffre V, Laccourreye H, Brasnu D . Complications and functional outcome after supracricoid partial laryngectomy with cricohyoidoepiglottopexy. Otolaryngol Head Neck Surg. 1998; 118(1):124-9. DOI: 10.1016/S0194-5998(98)70388-2. View

13.

Farrag T, Koch W, Cummings C, Goldenberg D, Abou-Jaoude P, Califano J . Supracricoid laryngectomy outcomes: The Johns Hopkins experience. Laryngoscope. 2007; 117(1):129-32. DOI: 10.1097/01.mlg.0000247660.47625.02. View

14.

Dedivitis R, Aires F, Cernea C, Brandao L . Pharyngocutaneous fistula after total laryngectomy: systematic review of risk factors. Head Neck. 2014; 37(11):1691-7. DOI: 10.1002/hed.23804. View

15.

Bryant G, Poulsen M, Tripcony L, Dickie G . Treatment decisions in T3N0M0 glottic carcinoma. Int J Radiat Oncol Biol Phys. 1995; 31(2):285-93. DOI: 10.1016/0360-3016(94)E0172-G. View

16.

Goor K, Peeters A, Mahieu H, Langendijk J, Leemans C, Verdonck-de Leeuw I . Cordectomy by CO2 laser or radiotherapy for small T1a glottic carcinomas: costs, local control, survival, quality of life, and voice quality. Head Neck. 2006; 29(2):128-36. DOI: 10.1002/hed.20500. View

17.

Pinar E, Imre A, Calli C, Oncel S, Katilmis H . Supracricoid partial laryngectomy: analyses of oncologic and functional outcomes. Otolaryngol Head Neck Surg. 2012; 147(6):1093-8. DOI: 10.1177/0194599812457334. View

18.

Ansarin M, Zorzi S, Massaro M, Tagliabue M, Proh M, Giugliano G . Transoral robotic surgery vs transoral laser microsurgery for resection of supraglottic cancer: a pilot surgery. Int J Med Robot. 2013; 10(1):107-12. DOI: 10.1002/rcs.1546. View

19.

Canis M, Ihler F, Martin A, Wolff H, Matthias C, Steiner W . Organ preservation in T4a laryngeal cancer: is transoral laser microsurgery an option?. Eur Arch Otorhinolaryngol. 2013; 270(10):2719-27. PMC: 3758515. DOI: 10.1007/s00405-013-2382-7. View

20.

Goncalves A, de Souza Jr J, Menezes M, Kavabata N, Suehara A, Lehn C . Pharyngocutaneous fistulae following total laryngectomy comparison between manual and mechanical sutures. Eur Arch Otorhinolaryngol. 2009; 266(11):1793-8. DOI: 10.1007/s00405-009-0945-4. View