An LRR/Malectin Receptor-Like Kinase Mediates Resistance to Non-adapted and Adapted Powdery Mildew Fungi in Barley and Wheat

Overview

Journal Front Plant Sci

Date 2016 Dec 27

PMID 28018377

Citations 21

Authors

Jeyaraman Rajaraman

Dimitar Douchkov

Gotz Hensel

Francesca L Stefanato

Anna Gordon

Nelzo Ereful

Octav F Caldararu

Andrei-Jose Petrescu

Jochen Kumlehn

Lesley A Boyd

Patrick Schweizer

Affiliations

Soon will be listed here.

Abstract

Pattern recognition receptors (PRRs) belonging to the multigene family of receptor-like kinases (RLKs) are the sensing devices of plants for microbe- or pathogen-associated molecular patterns released from microbial organisms. Here we describe (for ) encoding HvLEMK1, a LRR-malectin domain-containing transmembrane RLK that mediates non-host resistance of barley to the non-adapted wheat powdery mildew fungus f.sp. . Transgenic barley lines with silenced allow entry and colony growth of the non-adapted pathogen, although sporulation was reduced and final colony size did not reach that of the adapted barley powdery mildew fungus f.sp. . Transient expression of the barley or wheat genes enhanced resistance in wheat to the adapted wheat powdery mildew fungus while expression of the same genes did not protect barley from attack by the barley powdery mildew fungus. The results suggest that is a factor mediating non-host resistance in barley and quantitative host resistance in wheat to the wheat powdery mildew fungus.

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References

Tufan H, McGrann G, Magusin A, Morel J, Miche L, Boyd L . Wheat blast: histopathology and transcriptome reprogramming in response to adapted and nonadapted Magnaporthe isolates. New Phytol. 2009; 184(2):473-484. DOI: 10.1111/j.1469-8137.2009.02970.x. View

Hensel G, Valkov V, Middlefell-Williams J, Kumlehn J . Efficient generation of transgenic barley: the way forward to modulate plant-microbe interactions. J Plant Physiol. 2007; 165(1):71-82. DOI: 10.1016/j.jplph.2007.06.015. View

Sohn K, Saucet S, Clarke C, Vinatzer B, OBrien H, Guttman D . HopAS1 recognition significantly contributes to Arabidopsis nonhost resistance to Pseudomonas syringae pathogens. New Phytol. 2011; 193(1):58-66. DOI: 10.1111/j.1469-8137.2011.03950.x. View

Lacombe S, Rougon-Cardoso A, Sherwood E, Peeters N, Dahlbeck D, van Esse H . Interfamily transfer of a plant pattern-recognition receptor confers broad-spectrum bacterial resistance. Nat Biotechnol. 2010; 28(4):365-9. DOI: 10.1038/nbt.1613. View

Pawlowski M, Bogdanowicz A, Bujnicki J . QA-RecombineIt: a server for quality assessment and recombination of protein models. Nucleic Acids Res. 2013; 41(Web Server issue):W389-97. PMC: 3692112. DOI: 10.1093/nar/gkt408. View

Pennington H, Gheorghe D, Damerum A, Pliego C, Spanu P, Cramer R . Interactions between the Powdery Mildew Effector BEC1054 and Barley Proteins Identify Candidate Host Targets. J Proteome Res. 2016; 15(3):826-39. DOI: 10.1021/acs.jproteome.5b00732. View

Chen Y, Hu D, Yabe R, Tateno H, Qin S, Matsumoto N . Role of malectin in Glc(2)Man(9)GlcNAc(2)-dependent quality control of α1-antitrypsin. Mol Biol Cell. 2011; 22(19):3559-70. PMC: 3183012. DOI: 10.1091/mbc.E11-03-0201. View

Wicker T, Oberhaensli S, Parlange F, Buchmann J, Shatalina M, Roffler S . The wheat powdery mildew genome shows the unique evolution of an obligate biotroph. Nat Genet. 2013; 45(9):1092-6. DOI: 10.1038/ng.2704. View

Niehl A, Wyrsch I, Boller T, Heinlein M . Double-stranded RNAs induce a pattern-triggered immune signaling pathway in plants. New Phytol. 2016; 211(3):1008-19. DOI: 10.1111/nph.13944. View

10.

Nelson B, Cai X, Nebenfuhr A . A multicolored set of in vivo organelle markers for co-localization studies in Arabidopsis and other plants. Plant J. 2007; 51(6):1126-36. DOI: 10.1111/j.1365-313X.2007.03212.x. View

11.

Kaku H, Nishizawa Y, Ishii-Minami N, Akimoto-Tomiyama C, Dohmae N, Takio K . Plant cells recognize chitin fragments for defense signaling through a plasma membrane receptor. Proc Natl Acad Sci U S A. 2006; 103(29):11086-91. PMC: 1636686. DOI: 10.1073/pnas.0508882103. View

12.

Antolin-Llovera M, Petutsching E, Ried M, Lipka V, Nurnberger T, Robatzek S . Knowing your friends and foes--plant receptor-like kinases as initiators of symbiosis or defence. New Phytol. 2014; 204(4):791-802. DOI: 10.1111/nph.13117. View

13.

Brazma A, Hingamp P, Quackenbush J, Sherlock G, Spellman P, Stoeckert C . Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat Genet. 2001; 29(4):365-71. DOI: 10.1038/ng1201-365. View

14.

Wawra S, Belmonte R, Lobach L, Saraiva M, Willems A, van West P . Secretion, delivery and function of oomycete effector proteins. Curr Opin Microbiol. 2012; 15(6):685-91. DOI: 10.1016/j.mib.2012.10.008. View

15.

Chinchilla D, Zipfel C, Robatzek S, Kemmerling B, Nurnberger T, Jones J . A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence. Nature. 2007; 448(7152):497-500. DOI: 10.1038/nature05999. View

16.

Spies A, Korzun V, Bayles R, Rajaraman J, Himmelbach A, Hedley P . Allele mining in barley genetic resources reveals genes of race-non-specific powdery mildew resistance. Front Plant Sci. 2012; 2:113. PMC: 3355509. DOI: 10.3389/fpls.2011.00113. View

17.

Li C, Wu H, Cheung A . FERONIA and Her Pals: Functions and Mechanisms. Plant Physiol. 2016; 171(4):2379-92. PMC: 4972288. DOI: 10.1104/pp.16.00667. View

18.

Pliego C, Nowara D, Bonciani G, Gheorghe D, Xu R, Surana P . Host-induced gene silencing in barley powdery mildew reveals a class of ribonuclease-like effectors. Mol Plant Microbe Interact. 2013; 26(6):633-42. DOI: 10.1094/MPMI-01-13-0005-R. View

19.

Schweizer P . Tissue-specific expression of a defence-related peroxidase in transgenic wheat potentiates cell death in pathogen-attacked leaf epidermis. Mol Plant Pathol. 2008; 9(1):45-57. PMC: 6640441. DOI: 10.1111/j.1364-3703.2007.00446.x. View

20.

Li B, Meng X, Shan L, He P . Transcriptional Regulation of Pattern-Triggered Immunity in Plants. Cell Host Microbe. 2016; 19(5):641-50. PMC: 5049704. DOI: 10.1016/j.chom.2016.04.011. View