Plasma Free Reversible and Irreversible Microfluidic Bonding

Overview

Journal Lab Chip

Publisher Royal Society of Chemistry

Specialties Biotechnology
Chemistry

Date 2016 Dec 20

PMID 27990540

Citations 2

Authors

M Chu

T T Nguyen

E K Lee

J L Morival

M Khine

Affiliations

Soon will be listed here.

Abstract

We demonstrate a facile, plasma free process to fabricate both reversibly and irreversibly sealed microfluidic chips using a PDMS-based adhesive polymer mixture. This is a versatile method that is compatible with current PDMS microfluidics processes. It allows for easier fabrication of multilayer microfluidic devices and is compatible with micropatterning of proteins for cell culturing. When combined with our Shrinky-Dink microfluidic prototyping, complete microfluidic device fabrication can be performed without the need for any capital equipment, making microfluidics accessible to the classroom.

Citing Articles

Microfluidics chips fabrication techniques comparison.

Liu X, Sun A, Brodsky J, Gablech I, Lednicky T, Voparilova P Sci Rep. 2024; 14(1):28793.

PMID: 39567624 PMC: 11579384. DOI: 10.1038/s41598-024-80332-2.

Air-pressure-driven Separable Microdevice to Control the Anisotropic Curvature of Cell Culture Surface.

Yamashita T, Nishina T, Matsushita I, Sudo R Anal Sci. 2020; 36(8):1015-1019.

PMID: 32201406 DOI: 10.2116/analsci.20A001.

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