Comorbidity of Depression and Diabetes: an Application of Biopsychosocial Model

Overview

Journal Int J Ment Health Syst

Publisher Biomed Central

Specialty Health Services

Date 2016 Dec 17

PMID 27980612

Citations 7

Authors

Tesfa Dejenie Habtewold

Md Atiqul Islam

Yosef Tsige Radie

Balewgizie Sileshi Tegegne

Affiliations

Soon will be listed here.

Abstract

Background: Type 2 diabetes (T2D) is one of the most psychologically demanding chronic medical illness in adult. Comorbidity between diabetes and depression is quite common, but most studies were based on developed country sample. Limited data exists to document biopsychosocial predictors of depressive symptoms in Ethiopian patients. Therefore, the aim of the study was to describe the association of depressive symptoms and T2D and explore the potential underlying associated biopsychosocial risk factors.

Methods: Institution based cross-sectional study was conducted on 276 patient with T2D at diabetic clinic, Black Lion General Specialized Hospital in Ethiopia. Patients were selected using systematic random sampling technique. Depressive symptoms score, which constructed from a validated nine-item Patient Health Questionnaire (PHQ-9), was an outcome variable. Finally, significant associated factors were identified using multiple linear regression analysis with backward elimination procedure. Statistical Package for Social Science (SPSS) version 22.0 (IBM SPSS Corp.) was used to perform all analysis.

Results: Total of 264 patient data was analyzed with 95.7% response rate. Patients mean (SD) current age and age at diagnosis was 55.9 (10.9) and 43.9 (10.9) years, respectively. Patients waist circumference (mean ± SD) was 98.9 ± 11.1 cm. The average PHQ-9 score was 4.9 (SD 4.1) and fasting blood glucose was 166.4 (SD 73.2). Marital status (divorced), occupation (housewife), diabetic complication (nephropathy), negative life event in the last six months, and poor social support significantly associated with increased mean PHQ-9 score after adjustment for covariates. Whereas not fearing diabetic-related complication and death significantly lower mean PHQ-9 score.

Conclusion: Biopsychosocial variables including marital status, negative life event in the last 6 months, occupation, diabetic complication, and poor social support significantly increase average depressive symptoms score. Evidence-based intervention focusing on these identified biopsychosocial factors are necessary to prevent the development of depressive symptoms.

Citing Articles

Combined Effects of Smartphone Overdependence and Stress on Depression and Suicide-Related Behaviors among High School Students.

Kim H Healthcare (Basel). 2022; 10(9).

PMID: 36141284 PMC: 9498754. DOI: 10.3390/healthcare10091671.

Effects of traditional Chinese mind-body exercise-Baduanjin for type 2 diabetes on psychological well-being: A systematic review and meta-analysis.

Kong L, Ren J, Fang S, He T, Zhou X, Fang M Front Public Health. 2022; 10:923411.

PMID: 35968439 PMC: 9371619. DOI: 10.3389/fpubh.2022.923411.

Exploring Sexual Life Experiences and Perceptions of Women with Diabetes: A Qualitative Study.

Hoorsan R, Lamyian M, Ahmadi F, Azin S, Rahimiforoushani A Int J Community Based Nurs Midwifery. 2022; 10(3):223-233.

PMID: 35855381 PMC: 9287572. DOI: 10.30476/IJCBNM.2021.91530.1793.

SELF-CARE AND QUALITY OF LIFE PEOPLE WITH TYPE 2 DIABETES DURING THE COVID-19: CROSS-SECTIONAL STUDY.

Malini H, Zhahara S, Lenggogeni D, Putri Z J Diabetes Metab Disord. 2022; 21(1):785-790.

PMID: 35637659 PMC: 9134729. DOI: 10.1007/s40200-022-01055-7.

Biopsychosocial and Nutritional Factors of Depression among Type 2 Diabetes Mellitus Patients: A Systematic Review.

Amsah N, Md Isa Z, Ahmad N Int J Environ Res Public Health. 2022; 19(8).

PMID: 35457752 PMC: 9031597. DOI: 10.3390/ijerph19084888.

References

Kroenke K, Spitzer R, Williams J . The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001; 16(9):606-13. PMC: 1495268. DOI: 10.1046/j.1525-1497.2001.016009606.x. View

Siddiqui S . Depression in type 2 diabetes mellitus--a brief review. Diabetes Metab Syndr. 2014; 8(1):62-5. DOI: 10.1016/j.dsx.2013.06.010. View

Holt R, De Groot M, Golden S . Diabetes and depression. Curr Diab Rep. 2014; 14(6):491. PMC: 4476048. DOI: 10.1007/s11892-014-0491-3. View

de Groot M, Anderson R, Freedland K, Clouse R, Lustman P . Association of depression and diabetes complications: a meta-analysis. Psychosom Med. 2001; 63(4):619-30. DOI: 10.1097/00006842-200107000-00015. View

Ryerson B, Tierney E, Thompson T, Engelgau M, Wang J, Gregg E . Excess physical limitations among adults with diabetes in the U.S. population, 1997-1999. Diabetes Care. 2002; 26(1):206-10. DOI: 10.2337/diacare.26.1.206. View

Birhanu A, Alemu F, Ashenafie T, Balcha S, Dachew B . Depression in diabetic patients attending University of Gondar Hospital Diabetic Clinic, Northwest Ethiopia. Diabetes Metab Syndr Obes. 2016; 9:155-62. PMC: 4869639. DOI: 10.2147/DMSO.S97623. View

Akena D, Kadama P, Ashaba S, Akello C, Kwesiga B, Rejani L . The association between depression, quality of life, and the health care expenditure of patients with diabetes mellitus in Uganda. J Affect Disord. 2014; 174:7-12. PMC: 4549461. DOI: 10.1016/j.jad.2014.11.019. View

Zahid N, Asghar S, Claussen B, Hussain A . Depression and diabetes in a rural community in Pakistan. Diabetes Res Clin Pract. 2007; 79(1):124-7. DOI: 10.1016/j.diabres.2007.07.006. View

Schotte C, Van Den Bossche B, De Doncker D, Claes S, Cosyns P . A biopsychosocial model as a guide for psychoeducation and treatment of depression. Depress Anxiety. 2006; 23(5):312-24. DOI: 10.1002/da.20177. View

10.

Maia A, Braga A, Brouwers A, Nardi A, de Oliveira E Silva A . Prevalence of psychiatric disorders in patients with diabetes types 1 and 2. Compr Psychiatry. 2012; 53(8):1169-73. DOI: 10.1016/j.comppsych.2012.03.011. View

11.

Egede L, Ellis C . The effects of depression on diabetes knowledge, diabetes self-management, and perceived control in indigent patients with type 2 diabetes. Diabetes Technol Ther. 2008; 10(3):213-9. DOI: 10.1089/dia.2007.0278. View

12.

Roy T, Lloyd C, Parvin M, Mohiuddin K, Rahman M . Prevalence of co-morbid depression in out-patients with type 2 diabetes mellitus in Bangladesh. BMC Psychiatry. 2012; 12:123. PMC: 3502134. DOI: 10.1186/1471-244X-12-123. View

13.

Foran E, Hannigan A, Glynn L . Prevalence of depression in patients with type 2 diabetes mellitus in Irish primary care and the impact of depression on the control of diabetes. Ir J Med Sci. 2014; 184(2):319-22. DOI: 10.1007/s11845-014-1110-7. View

14.

Lloyd C, Sartorius N, Cimino L, Alvarez A, de Braude M, Rabbani G . The INTERPRET-DD study of diabetes and depression: a protocol. Diabet Med. 2015; 32(7):925-34. DOI: 10.1111/dme.12719. View

15.

Zhang W, Xu H, Zhao S, Yin S, Wang X, Guo J . Prevalence and influencing factors of co-morbid depression in patients with type 2 diabetes mellitus: a General Hospital based study. Diabetol Metab Syndr. 2015; 7:60. PMC: 4499190. DOI: 10.1186/s13098-015-0053-0. View

16.

Pouwer F, Geelhoed-Duijvestijn P, Tack C, Bazelmans E, Beekman A, Heine R . Prevalence of comorbid depression is high in out-patients with Type 1 or Type 2 diabetes mellitus. Results from three out-patient clinics in the Netherlands. Diabet Med. 2010; 27(2):217-24. DOI: 10.1111/j.1464-5491.2009.02903.x. View

17.

Demmer R, Gelb S, Suglia S, Keyes K, Aiello A, Colombo P . Sex differences in the association between depression, anxiety, and type 2 diabetes mellitus. Psychosom Med. 2015; 77(4):467-77. PMC: 4431947. DOI: 10.1097/PSY.0000000000000169. View

18.

Ghaemi S . The rise and fall of the biopsychosocial model. Br J Psychiatry. 2009; 195(1):3-4. DOI: 10.1192/bjp.bp.109.063859. View

19.

Musselman D, Betan E, Larsen H, Phillips L . Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment. Biol Psychiatry. 2003; 54(3):317-29. DOI: 10.1016/s0006-3223(03)00569-9. View

20.

Khan M, Sultan S, Nazli R, Akhtar T, Khan M, Sher N . Depression among patients with type-II diabetes mellitus. J Coll Physicians Surg Pak. 2014; 24(10):770-1. DOI: 10.2014/JCPSP.770771. View