Pathophysiology of Non Alcoholic Fatty Liver Disease

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2016 Dec 16

PMID 27973438

Citations 62

Authors

Salvatore Petta

Amalia Gastaldelli

Eleni Rebelos

Elisabetta Bugianesi

Piergiorgio Messa

Luca Miele

Gianluca Svegliati-Baroni

Luca Valenti

Ferruccio Bonino

Affiliations

Soon will be listed here.

Abstract

The physiopathology of fatty liver and metabolic syndrome are influenced by diet, life style and inflammation, which have a major impact on the severity of the clinicopathologic outcome of non-alcoholic fatty liver disease. A short comprehensive review is provided on current knowledge of the pathophysiological interplay among major circulating effectors/mediators of fatty liver, such as circulating lipids, mediators released by adipose, muscle and liver tissues and pancreatic and gut hormones in relation to diet, exercise and inflammation.

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