Bacteriophage WO Can Mediate Horizontal Gene Transfer in Endosymbiotic Genomes

Overview

Journal Front Microbiol

Specialty Microbiology

Date 2016 Dec 15

PMID 27965627

Citations 17

Authors

Guan H Wang

Bao F Sun

Tuan L Xiong

Yan K Wang

Kristen E Murfin

Jin H Xiao

Da W Huang

Affiliations

Soon will be listed here.

Abstract

Phage-mediated horizontal gene transfer (HGT) is common in free-living bacteria, and many transferred genes can play a significant role in their new bacterial hosts. However, there are few reports concerning phage-mediated HGT in endosymbionts (obligate intracellular bacteria within animal or plant hosts), such as . The -infecting temperate phage WO can actively shift among genomes and has the potential to mediate HGT between strains. In the present study, we extend previous findings by validating that the phage WO can mediate transfer of non-phage genes. To do so, we utilized bioinformatic, phylogenetic, and molecular analyses based on all sequenced and phage WO genomes. Our results show that the phage WO can mediate HGT between strains, regardless of whether the transferred genes originate from or other unrelated bacteria.

Citing Articles

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Luo Q, Li Y, Ren Y, Yang X, Zhu D Front Microbiol. 2025; 15():1499315.

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Intra-lineage microevolution of Wolbachia leads to the emergence of new cytoplasmic incompatibility patterns.

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analysis of the mobilome of a highly fragmented and repetitive genome reveals ongoing lateral gene transfer in an obligate intracellular bacterium.

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High Levels of Multiple Phage WO Infections and Its Evolutionary Dynamics Associated With -Infected Butterflies.

Gao S, Ren Y, Su C, Zhu D Front Microbiol. 2022; 13:865227.

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Prophage-mediated genome differentiation of the Derby ST71 population.

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