Technique Failure in Korean Incident Peritoneal Dialysis Patients: a National Population-based Study

Overview

Journal Kidney Res Clin Pract

Specialty Nephrology

Date 2016 Dec 14

PMID 27957420

Citations 6

Authors

Shina Lee

Hyunwook Kim

Kyoung Hoon Kim

Hoo Jae Hann

Hyeong Sik Ahn

Seung-Jung Kim

Duk-Hee Kang

Kyu Bok Choi

Dong-Ryeol Ryu

Affiliations

Soon will be listed here.

Abstract

Background: Technique failure is an important issue for peritoneal dialysis (PD) patients. In this study, we aimed to analyze technique failure rate in detail and to determine the predictors for technique failure in Korea.

Methods: We identified all patients who had started dialysis between January 1, 2005, and December 31, 2008, in Korea, using the Korean Health Insurance Review and Assessment Service database. A total of 7,614 PD patients were included, and the median follow-up was 24.9 months.

Results: The crude incidence rates of technique failure in PD patients were 54.1 per 1,000 patient-years. The cumulative 1-, 2-, and 3-year technique failure rates of PD patients were 4.9%, 10.3%, and 15.6%, respectively. However, those technique failure rates by Kaplan-Meier analysis were overestimated compared with the values by competing risks analysis, and the differences increased with the follow-up period. In multivariate analyses, diabetes mellitus and Medical Aid as a crude reflection of low socioeconomic status were independent risk factors in both the Cox proportional hazard model and Fine and Gray subdistribution model. In addition, cancer was independently associated with a lower risk of technique failure in the Fine and Gray model.

Conclusion: Technique failure was a major concern in patients initiating PD in Korea, especially in diabetic patients and Medical Aid beneficiaries. The results of our study offer a basis for risk stratification for technique failure.

Citing Articles

Home hemodialysis technique survival: insights and challenges.

Tran E, Karadjian O, Chan C, Trinh E BMC Nephrol. 2023; 24(1):205.

PMID: 37434110 PMC: 10337160. DOI: 10.1186/s12882-023-03264-5.

Incidence and Risk Factors Associated with Technique Failure in the First Year of Peritoneal Dialysis: A Single Center Retrospective Cohort Study in Southern China.

Dong X, Wu H, Ye H, Yi C, Diao X, Liu R BMC Nephrol. 2022; 23(1):207.

PMID: 35690721 PMC: 9188716. DOI: 10.1186/s12882-022-02833-4.

Epidemiological characteristics of cancers in patients with end-stage kidney disease: a Korean nationwide study.

Lee M, Lee E, Park B, Park I Sci Rep. 2021; 11(1):3929.

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Clinical outcomes of infection-related hospitalization in incident peritoneal dialysis patients.

Jeon Y, Kim H, Hong Y, Kim H, Yang C, Chang Y Kidney Res Clin Pract. 2020; 39(4):460-468.

PMID: 33184240 PMC: 7770989. DOI: 10.23876/j.krcp.20.069.

Incremental Peritoneal Dialysis May be Beneficial for Preserving Residual Renal Function Compared to Full-dose Peritoneal Dialysis.

Lee Y, Chung S, Park S, Ryu H, Lee H, Kim D Sci Rep. 2019; 9(1):10105.

PMID: 31300708 PMC: 6626037. DOI: 10.1038/s41598-019-46654-2.

References

Chidambaram M, Bargman J, Quinn R, Austin P, Hux J, Laupacis A . Patient and physician predictors of peritoneal dialysis technique failure: a population based, retrospective cohort study. Perit Dial Int. 2010; 31(5):565-73. DOI: 10.3747/pdi.2010.00096. View

Han S, Lee J, Kim D, Moon S, Kim H, Chang J . Long-term clinical outcomes of peritoneal dialysis patients: single center experience from Korea. Perit Dial Int. 2008; 28 Suppl 3:S21-6. View

Descoeudres B, Koller M, Garzoni D, Wolff T, Steiger J, Schaub S . Contribution of early failure to outcome on peritoneal dialysis. Perit Dial Int. 2008; 28(3):259-67. View

Fraser S, Roderick P, Casey M, Taal M, Yuen H, Nutbeam D . Prevalence and associations of limited health literacy in chronic kidney disease: a systematic review. Nephrol Dial Transplant. 2012; 28(1):129-37. DOI: 10.1093/ndt/gfs371. View

Teixeira L, Rodrigues A, Carvalho M, Cabrita A, Mendonca D . Modelling competing risks in nephrology research: an example in peritoneal dialysis. BMC Nephrol. 2013; 14:110. PMC: 3664602. DOI: 10.1186/1471-2369-14-110. View

Choi H, Kim M, Kim H, Lee J, Lee J, Park J . Excess mortality among patients on dialysis: Comparison with the general population in Korea. Kidney Res Clin Pract. 2016; 33(2):89-94. PMC: 4714183. DOI: 10.1016/j.krcp.2014.04.001. View

Cotovio P, Rocha A, Carvalho M, Teixeira L, Mendonca D, Cabrita A . Better outcomes of peritoneal dialysis in diabetic patients in spite of risk of loss of autonomy for home dialysis. Perit Dial Int. 2014; 34(7):775-80. PMC: 4269503. DOI: 10.3747/pdi.2012.00111. View

Jin D, Han J . Renal replacement therapy in Korea, 2012. Kidney Res Clin Pract. 2016; 33(1):9-18. PMC: 4714170. DOI: 10.1016/j.krcp.2014.01.002. View

Konner K . Primary vascular access in diabetic patients: an audit. Nephrol Dial Transplant. 2000; 15(9):1317-25. DOI: 10.1093/ndt/15.9.1317. View

10.

Kim H, Kim K, Park K, Kang S, Yoo T, Ahn S . A population-based approach indicates an overall higher patient mortality with peritoneal dialysis compared to hemodialysis in Korea. Kidney Int. 2014; 86(5):991-1000. DOI: 10.1038/ki.2014.163. View

11.

Beuscart J, Pagniez D, Boulanger E, Lessore De Sainte Foy C, Salleron J, Frimat L . Overestimation of the probability of death on peritoneal dialysis by the Kaplan-Meier method: advantages of a competing risks approach. BMC Nephrol. 2012; 13:31. PMC: 3500245. DOI: 10.1186/1471-2369-13-31. View

12.

Jager K, Merkus M, Dekker F, Boeschoten E, Tijssen J, Stevens P . Mortality and technique failure in patients starting chronic peritoneal dialysis: results of The Netherlands Cooperative Study on the Adequacy of Dialysis. NECOSAD Study Group. Kidney Int. 1999; 55(4):1476-85. DOI: 10.1046/j.1523-1755.1999.00353.x. View

13.

Kumar V, Sidell M, Yang W, Jones J . Predictors of peritonitis, hospital days, and technique survival for peritoneal dialysis patients in a managed care setting. Perit Dial Int. 2013; 34(2):171-8. PMC: 3968102. DOI: 10.3747/pdi.2012.00165. View

14.

Schaubel D, Blake P, Fenton S . Effect of renal center characteristics on mortality and technique failure on peritoneal dialysis. Kidney Int. 2001; 60(4):1517-24. DOI: 10.1046/j.1523-1755.2001.00969.x. View

15.

Wong J, Port F, Carroll C, Wolfe R, Agodoa L, Daugirdas J . Survival advantage in Asian American end-stage renal disease patients. Kidney Int. 1999; 55(6):2515-23. DOI: 10.1046/j.1523-1755.1999.00464.x. View

16.

Pajek J, Hutchison A, Bhutani S, Brenchley P, Hurst H, Pohar Perme M . Outcomes of peritoneal dialysis patients and switching to hemodialysis: a competing risks analysis. Perit Dial Int. 2014; 34(3):289-98. PMC: 4033329. DOI: 10.3747/pdi.2012.00248. View

17.

Charlson M, Pompei P, Ales K, MacKenzie C . A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987; 40(5):373-83. DOI: 10.1016/0021-9681(87)90171-8. View

18.

Quan H, Sundararajan V, Halfon P, Fong A, Burnand B, Luthi J . Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care. 2005; 43(11):1130-9. DOI: 10.1097/01.mlr.0000182534.19832.83. View

19.

Bastos K, Qureshi A, Lopes A, Fernandes N, Barbosa L, Pecoits-Filho R . Family income and survival in Brazilian Peritoneal Dialysis Multicenter Study Patients (BRAZPD): time to revisit a myth?. Clin J Am Soc Nephrol. 2011; 6(7):1676-83. DOI: 10.2215/CJN.09041010. View

20.

Fang W, Yang X, Kothari J, Khandelwal M, Naimark D, Jassal S . Patient and technique survival of diabetics on peritoneal dialysis: one-center's experience and review of the literature. Clin Nephrol. 2008; 69(3):193-200. DOI: 10.5414/cnp69193. View