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Bimatoprost Induced Serous Macular Detachment After Cataract Surgery

Overview
Publisher Wiley
Specialty Ophthalmology
Date 2016 Dec 14
PMID 27957367
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Abstract

We report a case of bimatoprost induced serous macular detachment and choroidal folds following uneventful cataract surgery. A 66-year-old male using topical bimatoprost in both eyes for open angle glaucoma underwent uneventful cataract surgery in the right eye. Postoperatively, he was restarted on topical bimatoprost and antibiotic-steroids combination drops. One week after surgery, he presented with conjunctival hyperemia, serous macular detachment, and choroidal folds at the posterior pole. Fundus fluorescein angiography showed perifoveal leaks in early stage with pooling of dye in late stage. Discontinuation of bimatoprost led to resolution of serous detachment and choroidal folds within 3 weeks with significant improvement in visual acuity. Occurrence of serous macular detachment and choroidal folds in this case could be probably related to the proinflammatory property of bimatoprost. Hence, it should be used with caution in the immediate postoperative period after cataract surgery.

References
1.
Alm A, Grierson I, Shields M . Side effects associated with prostaglandin analog therapy. Surv Ophthalmol. 2008; 53 Suppl1:S93-105. DOI: 10.1016/j.survophthal.2008.08.004. View

2.
Vinores S, Sen H, Campochiaro P . An adenosine agonist and prostaglandin E1 cause breakdown of the blood-retinal barrier by opening tight junctions between vascular endothelial cells. Invest Ophthalmol Vis Sci. 1992; 33(6):1870-8. View

3.
Addison P, Papadopoulos M, Nischal K, Hykin P . Serous retinal detachment induced by topical bimatoprost in a patient with Sturge-Weber syndrome. Eye (Lond). 2010; 25(1):124-5. PMC: 3144641. DOI: 10.1038/eye.2010.191. View

4.
Yousufzai S, Ye Z, Abdel-Latif A . Prostaglandin F2 alpha and its analogs induce release of endogenous prostaglandins in iris and ciliary muscles isolated from cat and other mammalian species. Exp Eye Res. 1996; 63(3):305-10. DOI: 10.1006/exer.1996.0119. View

5.
Toris C, Gabelt B, Kaufman P . Update on the mechanism of action of topical prostaglandins for intraocular pressure reduction. Surv Ophthalmol. 2008; 53 Suppl1:S107-20. PMC: 2727743. DOI: 10.1016/j.survophthal.2008.08.010. View