Morphological Differences Between Optic Disc Collaterals and Neovascularization on Optical Coherence Tomography Angiography

Overview

Journal Graefes Arch Clin Exp Ophthalmol

Specialty Ophthalmology

Date 2016 Dec 13

PMID 27942950

Citations 13

Authors

Ankur Singh

Aniruddha Agarwal

Sarakshi Mahajan

Samendra Karkhur

Ramandeep Singh

Reema Bansal

Mangat R Dogra

Vishali Gupta

Affiliations

Soon will be listed here.

Abstract

Background: To study morphological features of optic disc venous collaterals (OVCs) and neovascularization of optic disc (NVD) on optical coherence tomography angiography (OCTA).

Methods: Patients with OVCs and NVDs secondary to ischemic retinal diseases were prospectively enrolled. Multimodal imaging was performed using color fundus photography, fluorescein angiography (FA), and OCTA. Morphological evaluation of en-face structural OCT, cross-sectional and en-face OCTA was performed.

Results: Twenty eyes (20 patients; OVCs: n = 10 and NVD: n = 10) were included. OVCs appeared as small, loopy vessels distinct from surrounding peripapillary capillaries on OCTA in the radial peripapillary capillary frame. NVDs appeared as a mesh of fine caliber, raised vessels best seen in the vitreous slab of OCTA. Flow signals in these vascular alterations correlated well with hyperfluorescence on FA.

Conclusions: OCTA provides improved visualization of NVDs and OVCs in ischemic retinal diseases such as diabetic retinopathy and retinal vein occlusions compared to conventional FA.

Citing Articles

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Optociliary Shunt Vessels or Neovascularisation of the Optic Disc: Fluorescein Angiography Versus Optical Coherence Tomography Angiography.

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Luo M, Li Y, Zhuo Y Front Med (Lausanne). 2021; 8:721442.

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Assessment of the retinal vasculature in healthy Chinese preschool children aged 4-6 years old using optical coherence tomography angiography.

Xiang L, Zhou Y, Chen Y, Jiang S, Fei C, Wang Y BMC Ophthalmol. 2021; 21(1):415.

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Role of optical coherence tomography-angiography in diabetes mellitus: Utility in diabetic retinopathy and a comparison with fluorescein angiography in vision threatening diabetic retinopathy.

Shaikh N, Vohra R, Balaji A, Azad S, Chawla R, Kumar V Indian J Ophthalmol. 2021; 69(11):3218-3224.

PMID: 34708776 PMC: 8725072. DOI: 10.4103/ijo.IJO_1267_21.

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