Buspirone Therapy for Maladaptive Behavior and Anxiety in Developmentally Disabled Persons
Overview
Authors
Affiliations
The authors used buspirone, a new anxiolytic agent that has a low side effect profile, to treat 14 developmentally disabled individuals who demonstrated anxiety as well as aggressive and self-injurious behaviors. Nine of the 14 individuals responded favorably to the drug. The authors present case reports for 3 of the responders and discuss the clinical implications of buspirone therapy.
Jaipal A, Pandey M, Charde S, Raut P, Prasanth K, Prasad R Saudi Pharm J. 2015; 23(3):315-26.
PMID: 26106280 PMC: 4475836. DOI: 10.1016/j.jsps.2014.11.012.
Minshawi N, Hurwitz S, Morriss D, McDougle C J Autism Dev Disord. 2014; 45(6):1541-68.
PMID: 25395094 DOI: 10.1007/s10803-014-2307-3.
Devine D Psychopharmacology (Berl). 2013; 231(6):979-97.
PMID: 24057764 DOI: 10.1007/s00213-013-3279-2.
Brain serotonin receptors and transporters: initiation vs. termination of escalated aggression.
Takahashi A, Quadros I, de Almeida R, Miczek K Psychopharmacology (Berl). 2010; 213(2-3):183-212.
PMID: 20938650 PMC: 3684010. DOI: 10.1007/s00213-010-2000-y.
Davis E, Saeed S, Antonacci D Psychiatr Q. 2008; 79(3):249-63.
PMID: 18726156 DOI: 10.1007/s11126-008-9081-3.