Recent Progress in Electrochemical Biosensors for Glycoproteins
Overview
Authors
Affiliations
This review provides an overview of recent progress in the development of electrochemical biosensors for glycoproteins. Electrochemical glycoprotein sensors are constructed by combining metal and carbon electrodes with glycoprotein-selective binding elements including antibodies, lectin, phenylboronic acid and molecularly imprinted polymers. A recent trend in the preparation of glycoprotein sensors is the successful use of nanomaterials such as graphene, carbon nanotube, and metal nanoparticles. These nanomaterials are extremely useful for improving the sensitivity of glycoprotein sensors. This review focuses mainly on the protocols for the preparation of glycoprotein sensors and the materials used. Recent improvements in glycoprotein sensors are discussed by grouping the sensors into several categories based on the materials used as recognition elements.
Site-Specific Immobilization Boosts the Performance of a Galectin-1 Biosensor.
Kolanovic D, Pasupuleti R, Wallner J, Mlynek G, Wiltschi B Bioconjug Chem. 2024; 35(12):1944-1958.
PMID: 39625149 PMC: 11660155. DOI: 10.1021/acs.bioconjchem.4c00467.
Oliveira D, Barcelay Y, Moreira F RSC Adv. 2024; 14(22):15347-15357.
PMID: 38741963 PMC: 11089526. DOI: 10.1039/d4ra02051k.
Biosensors with Boronic Acid-Based Materials as the Recognition Elements and Signal Labels.
Liu L, Ma X, Chang Y, Guo H, Wang W Biosensors (Basel). 2023; 13(8).
PMID: 37622871 PMC: 10452607. DOI: 10.3390/bios13080785.
Sondhi P, Neupane D, Bhattarai J, Demchenko A, Stine K J Electroanal Chem (Lausanne). 2022; 924.
PMID: 36405880 PMC: 9673609. DOI: 10.1016/j.jelechem.2022.116865.
Molecular imprinting of glycoproteins: From preparation to cancer theranostics.
Ali M, Zhu S, Amin F, Hussain D, Du Z, Hu L Theranostics. 2022; 12(5):2406-2426.
PMID: 35265217 PMC: 8899583. DOI: 10.7150/thno.69189.