Outcome of Acute Kidney Injury in Critical Care Unit, Based on AKI Network

Overview

Journal Tanaffos

Specialty Pulmonary Medicine

Date 2016 Dec 2

PMID 27904540

Citations 8

Authors

Seyed Mohammadreza Hashemian

Hamidreza Jamaati

Behrooz Farzanegan Bidgoli

Farin Rashid Farrokhi

Majid Malekmohammad

Sepehr Roozdar

Seyed Amir Mohajerani

Ahmad Bagheri

Golnar Radmnand

Behzad Hatami

Mandana Chitsazan

Affiliations

Soon will be listed here.

Abstract

Background: Acute Kidney Injury (AKI) is an unsolved clinical problem in critical care patients with a high mortality rate, increasing incidence, and no definitive therapy. We studied the incidence, risk factors, and mortality associated with AKI in ICU patients.

Materials And Methods: In a prospective study, patient demographics, reason for hospitalization, reason for ICU admission, Length of ICU stay, laboratory data, and Vital signs were recorded in prepared forms during the ICU stay. AKI was defined as an increase in serum creatinine (SCr) of ≥ 0.3mg/dl from the baseline.

Results: A total of 200 patients who were enrolled in our study; 134 (67%) did not develop AKI during their ICU stay while 66 (33%) developed AKI (SCr ≥ 0.3) according to the AKIN definition. Patients with AKI had higher APACHE II scores (12.3±5.6 vs. 6.9±3.6; P< 0.001), longer ICU stays (7.6±7.6 vs. 3.7±2.8 days respectively; P< 0.001), and higher mortality (19.7% vs. 0.7%; P< 0.001).

Conclusion: The AKIN criteria are clinically valid and can be a good predictor of mortality and patient outcome in addition to APACHE II score in ICU patients.

Citing Articles

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Prevalence and Mortality Rates of Acute Kidney Injury among Critically Ill Patients: A Retrospective Study.

Farah R, Alfuqaha O, Younes A, Mahmoud H, Al-Jboor A, Karajeh M Crit Care Res Pract. 2023; 2023:9966760.

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Validated risk prediction models for outcomes of acute kidney injury: a systematic review.

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Factors Associated with ICU Mortality at Hawassa University Comprehensive Specialized Hospital (HUCSH).

Wotiye A, Shimber E, Ayele B Ethiop J Health Sci. 2022; 32(3):505-512.

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Assessment of APACHE II Score to Predict ICU Outcomes of Patients with AKI: A Single-center Experience from Haryana, North India.

Patel P, Gupta S, Patel H, Bashar M Indian J Crit Care Med. 2022; 26(3):276-281.

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