An Ir(III) Complex Chemosensor for the Detection of Thiols

Overview

Journal Sci Technol Adv Mater

Specialty Biomedical Engineering

Date 2016 Nov 24

PMID 27877862

Citations 6

Authors

Zhifeng Mao

Jinbiao Liu

Tian-Shu Kang

Wanhe Wang

Quan-Bin Han

Chun-Ming Wang

Chung-Hang Leung

Dik-Lung Ma

Affiliations

Soon will be listed here.

Abstract

In this study, we report the use of a cyclometalated luminescent iridium(III) complex for the visualization of thiols. The detection of glutathione (GSH) by complex is achieved through the reduction of its phendione N^N donor, which influences the metal-to-ligand charge-transfer (MLCT) of the complex. Complex produced a maximum threefold luminescence enhancement at 587 nm in response to GSH. The linear detection range of for GSH is between 0.2 and 2 M equivalents of GSH, with a detection limit of 1.67 μM. Complex also displays good selectivity for thiols over other amino acids.

Citing Articles

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The chronological evolution of small organic molecular fluorescent probes for thiols.

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Luminescent chemosensors by using cyclometalated iridium(iii) complexes and their applications.

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