Hydroxylapatite Nanoparticles: Fabrication Methods and Medical Applications

Overview

Journal Sci Technol Adv Mater

Specialty Biomedical Engineering

Date 2016 Nov 24

PMID 27877527

Citations 17

Authors

Masahiro Okada

Tsutomu Furuzono

Affiliations

Soon will be listed here.

Abstract

Hydroxylapatite (or hydroxyapatite, HAp) exhibits excellent biocompatibility with various kinds of cells and tissues, making it an ideal candidate for tissue engineering, orthopedic and dental applications. Nanosized materials offer improved performances compared with conventional materials due to their large surface-to-volume ratios. This review summarizes existing knowledge and recent progress in fabrication methods of nanosized (or nanostructured) HAp particles, as well as their recent applications in medical and dental fields. In section 1, we provide a brief overview of HAp and nanoparticles. In section 2, fabrication methods of HAp nanoparticles are described based on the particle formation mechanisms. Recent applications of HAp nanoparticles are summarized in section 3. The future perspectives in this active research area are given in section 4.

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