Comparison of the Effect of Lidocaine Versus a Lidocaine-Bupivacaine Combination in a Periprostatic Nerve Block Undergoing Transrectal Ultrasound-Guided Prostate Biopsy: A Double-Blind Randomized Controlled Trial

Overview

Journal Curr Urol

Specialty Urology

Date 2016 Nov 22

PMID 27867334

Citations 1

Authors

Ali H Yilmaz

Elif Ziypak

Tevfik Ziypak

Mehmet Aksoy

Senol Adanur

Huseyin Kocakgol

Saban O Demirdogen

Ozkan Polat

Affiliations

Soon will be listed here.

Abstract

Introduction: To determine whether a combination of the long acting local anesthetic, bupivacaine, and lidocaine is better than lidocaine alone in the long-term pain control, which is a short-acting anesthetic.

Materials And Methods: In group 1, periprostatic nerve block was applied to both neurovascular areas with 2% lidocaine (5 ml) in an isotonic solution (5 ml). In group 2, the combination of 2% lidocaine (5 ml) and 5mg/ml bupivacaine (5 ml) was used for the PPNB.

Results: In the first 30 minutes the mean VAS scores of groups 1 and 2 were 2.1 ± 0.2 and 1.2 ± 0.1, respectively (p = 0.002). VAS scores of group II determined at 1, 2, 4, 6, and 8 hours after the biopsy were significantly lower since it was (p < 0.05).

Conclusion: While periprostatic nerve block for late phase pain control, applying a combination of a long-acting local anesthetic, such as bupivacaine, is effective in terms of pain control and patient comfort.

Citing Articles

Effectiveness of periprostatic block to prevent pain in transrectal prostate biopsy: a systematic review and a network meta-analysis.

Garcia-Perdomo H, Mejia N, Fernandez L, Carbonell J Cent European J Urol. 2019; 72(2):121-133.

PMID: 31482018 PMC: 6715078. DOI: 10.5173/ceju.2019.1874.

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