Spanish Modified Version of the Palliative Care Outcome Scale-symptoms Renal: Cross-cultural Adaptation and Validation

Overview

Journal BMC Nephrol

Publisher Biomed Central

Specialty Nephrology

Date 2016 Nov 20

PMID 27863475

Citations 6

Authors

Daniel Gutierrez-Sanchez

Juan P Leiva-Santos

Rosa Sanchez-Hernandez

Domingo Hernandez-Marrero

Antonio I Cuesta-Vargas

Affiliations

Soon will be listed here.

Abstract

Background: Patients with chronic kidney disease (CKD) have a high symptoms burden that is related to a poor health-related quality of life (HRQoL) and high costs of care. Validated instruments may be useful for assessing the symptoms and monitoring outcomes in these patients. The Palliative care Outcome Scale-Symptoms Renal (POS-S Renal) is a patient-reported outcome measure for assessing symptoms in CKD stage 4-5. This study is the first cross-cultural adaptation and psychometric analysis of this clinical tool. The purpose of this study is to carry out a cross-cultural adaptation of the POS-S Renal for Spanish-speaking patients, and to perform an analysis of the psychometric properties of this questionnaire.

Methods: The English version of the POS-S Renal was culturally adapted and translated into Spanish using a double forward and backward method. An expert panel evaluated the content validity. The questionnaire was pilot-tested in 30 patients. A total of 200 patients with CKD stage 4-5 filled in a modified Spanish version of the POS-S Renal and the MSAS-SF. Statistical analysis to evaluate the psychometric properties of the questionnaire was carried out.

Results: The content validity index (CVI) was 0.97, which indicated that the content of the instrument is an adequate reflection of the symptoms in advanced CKD (ACKD). The factor analysis indicated a two-factor solution explaining 35.05% of total variance. The confirmatory factor analysis (CFA) demonstrated that the two factor model was well supported (comparative fit index = 0.98, root mean square error of approximation = 0.068). This assessment tool demonstrated a satisfactory test-retest reliability (r = 0.909 to factor 1, r = 0.695 to factor 2, r = 0.887 to total score), good internal consistency to factor 1 (α = 0.78) and moderate internal consistency to factor 2 (α = 0.56). Concurrent criterion-related validity with MSAS-SF was also demonstrated, with r = 0.860, which indicated a high degree of correlation with a validated instrument that has been used in patients with ACKD.

Conclusions: The Spanish modified version of the POS-S Renal is a reliable and valid instrument that can be used to assess symptoms in Spanish patients with CKD stage 4-5.

Citing Articles

Cluster of symptoms in kidney failure: A systematic review.

Gomariz-Ruiz J, Perez-Cruzado D, Gutierrez-Sanchez D Heliyon. 2025; 11(1):e41556.

PMID: 39845015 PMC: 11750532. DOI: 10.1016/j.heliyon.2024.e41556.

Consensus document on palliative care in cardiorenal patients.

Bonanad C, Buades J, Leiva J, de la Espriella R, Marcos M, Nunez J Front Cardiovasc Med. 2024; 10:1225823.

PMID: 38179502 PMC: 10766370. DOI: 10.3389/fcvm.2023.1225823.

Kannada Translation and Validation of the ESAS-r Renal for Symptom Burden Survey in Patients with End-Stage Kidney Disease.

Naik B, Nagaraju S, Guddattu V, Salins N, Prabhu R, Damani A Indian J Palliat Care. 2023; 29(2):195-199.

PMID: 37325264 PMC: 10261939. DOI: 10.25259/IJPC_216_2022.

Quality of Life and Related Factors in Patients Undergoing Renal Replacement Therapy at the Hospital General Universitario de Ciudad Real: Cross Sectional Descriptive Observational Study.

Berenguer-Martinez J, Bernal-Celestino R, Leon-Martin A, Gonzalez-Moro M, Fernandez-Calvo N, Arias-Del-Campo L J Clin Med. 2023; 12(6).

PMID: 36983250 PMC: 10058206. DOI: 10.3390/jcm12062250.

Development of a preliminary conceptual model of the patient experience of chronic kidney disease: a targeted literature review and analysis.

Flythe J, Karlsson N, Sundgren A, Cordero P, Grandinetti A, Cremisi H BMC Nephrol. 2021; 22(1):233.

PMID: 34162354 PMC: 8220773. DOI: 10.1186/s12882-021-02440-9.

References

Rocco M, Burkart J . Prevalence of missed treatments and early sign-offs in hemodialysis patients. J Am Soc Nephrol. 1993; 4(5):1178-83. DOI: 10.1681/ASN.V451178. View

Mokkink L, Terwee C, Patrick D, Alonso J, Stratford P, Knol D . The COSMIN checklist for assessing the methodological quality of studies on measurement properties of health status measurement instruments: an international Delphi study. Qual Life Res. 2010; 19(4):539-49. PMC: 2852520. DOI: 10.1007/s11136-010-9606-8. View

Almutary H, Bonner A, Douglas C . Arabic translation, adaptation and modification of the Dialysis Symptom Index for chronic kidney disease stages four and five. BMC Nephrol. 2015; 16:36. PMC: 4377038. DOI: 10.1186/s12882-015-0036-2. View

Davison S, Levin A, Moss A, Jha V, Brown E, Brennan F . Executive summary of the KDIGO Controversies Conference on Supportive Care in Chronic Kidney Disease: developing a roadmap to improving quality care. Kidney Int. 2015; 88(3):447-59. DOI: 10.1038/ki.2015.110. View

Muniz J, Elosua P, Hambleton R . [International Test Commission Guidelines for test translation and adaptation: second edition]. Psicothema. 2013; 25(2):151-7. DOI: 10.7334/psicothema2013.24. View

Murtagh F, Addington-Hall J, Higginson I . The prevalence of symptoms in end-stage renal disease: a systematic review. Adv Chronic Kidney Dis. 2007; 14(1):82-99. DOI: 10.1053/j.ackd.2006.10.001. View

Dapueto J, Abreu M, Francolino C, Levin R . Psychometric assessment of the MSAS-SF and the FACIT-Fatigue Scale in Spanish-speaking patients with cancer in Uruguay. J Pain Symptom Manage. 2013; 47(5):936-45. DOI: 10.1016/j.jpainsymman.2013.06.020. View

Weisbord S, Carmody S, Bruns F, Rotondi A, Cohen L, Zeidel M . Symptom burden, quality of life, advance care planning and the potential value of palliative care in severely ill haemodialysis patients. Nephrol Dial Transplant. 2003; 18(7):1345-52. DOI: 10.1093/ndt/gfg105. View

Perrone R, Coons S, Cavanaugh K, Finkelstein F, Meyer K . Patient-reported outcomes in clinical trials of CKD-related therapies: report of a symposium sponsored by the national kidney foundation and the U.S. Food and Drug Administration. Am J Kidney Dis. 2013; 62(6):1046-57. DOI: 10.1053/j.ajkd.2013.07.004. View

10.

Iyasere O, Brown E . Determinants of quality of life in advanced kidney disease: time to screen?. Postgrad Med J. 2014; 90(1064):340-7. DOI: 10.1136/postgradmedj-2013-132251. View

11.

Brown M, Crail S, Masterson R, Foote C, Robins J, Katz I . ANZSN renal supportive care 2013: opinion pieces [corrected]. Nephrology (Carlton). 2013; 18(6):401-454. DOI: 10.1111/nep.12065. View

12.

Portenoy R, Thaler H, Kornblith A, Lepore J, Kiyasu E, Sobel K . The Memorial Symptom Assessment Scale: an instrument for the evaluation of symptom prevalence, characteristics and distress. Eur J Cancer. 1994; 30A(9):1326-36. DOI: 10.1016/0959-8049(94)90182-1. View

13.

Callahan D . Death and the research imperative. N Engl J Med. 2000; 342(9):654-6. DOI: 10.1056/NEJM200003023420910. View

14.

Chang V, Hwang S, Feuerman M, Kasimis B, Thaler H . The memorial symptom assessment scale short form (MSAS-SF). Cancer. 2000; 89(5):1162-71. DOI: 10.1002/1097-0142(20000901)89:5<1162::aid-cncr26>3.0.co;2-y. View

15.

Weisbord S, Fried L, Arnold R, Rotondi A, Fine M, Levenson D . Development of a symptom assessment instrument for chronic hemodialysis patients: the Dialysis Symptom Index. J Pain Symptom Manage. 2004; 27(3):226-40. DOI: 10.1016/j.jpainsymman.2003.07.004. View

16.

Jablonski A . The multidimensional characteristics of symptoms reported by patients on hemodialysis. Nephrol Nurs J. 2007; 34(1):29-37. View

17.

Murphy E, Murtagh F, Carey I, Sheerin N . Understanding symptoms in patients with advanced chronic kidney disease managed without dialysis: use of a short patient-completed assessment tool. Nephron Clin Pract. 2008; 111(1):c74-80. DOI: 10.1159/000183177. View

18.

Murtagh F, Addington-Hall J, Edmonds P, Donohoe P, Carey I, Jenkins K . Symptoms in the month before death for stage 5 chronic kidney disease patients managed without dialysis. J Pain Symptom Manage. 2010; 40(3):342-52. DOI: 10.1016/j.jpainsymman.2010.01.021. View

19.

Murtagh F, Addington-Hall J, Edmonds P, Donohoe P, Carey I, Jenkins K . Symptoms in advanced renal disease: a cross-sectional survey of symptom prevalence in stage 5 chronic kidney disease managed without dialysis. J Palliat Med. 2007; 10(6):1266-76. DOI: 10.1089/jpm.2007.0017. View

20.

Alvarez-Ude F, Fernandez-Reyes M, Vazquez A, Mon C, Sanchez R, Rebollo P . [Physical symptoms and emotional disorders in patient on a periodic hemodialysis program]. Nefrologia. 2001; 21(2):191-9. View