Comparison of Conventional DCE-MRI and a Novel Golden-angle Radial Multicoil Compressed Sensing Method for the Evaluation of Breast Lesion Conspicuity

Overview

Journal J Magn Reson Imaging

Date 2016 Nov 19

PMID 27859874

Citations 17

Authors

Laura Heacock

Yiming Gao

Samantha L Heller

Amy N Melsaether

James S Babb

Tobias K Block

Ricardo Otazo

Sungheon G Kim

Linda Moy

Affiliations

Soon will be listed here.

Abstract

Purpose: To compare a novel multicoil compressed sensing technique with flexible temporal resolution, golden-angle radial sparse parallel (GRASP), to conventional fat-suppressed spoiled three-dimensional (3D) gradient-echo (volumetric interpolated breath-hold examination, VIBE) MRI in evaluating the conspicuity of benign and malignant breast lesions.

Materials And Methods: Between March and August 2015, 121 women (24-84 years; mean, 49.7 years) with 180 biopsy-proven benign and malignant lesions were imaged consecutively at 3.0 Tesla in a dynamic contrast-enhanced (DCE) MRI exam using sagittal T1-weighted fat-suppressed 3D VIBE in this Health Insurance Portability and Accountability Act-compliant, retrospective study. Subjects underwent MRI-guided breast biopsy (mean, 13 days [1-95 days]) using GRASP DCE-MRI, a fat-suppressed radial "stack-of-stars" 3D FLASH sequence with golden-angle ordering. Three readers independently evaluated breast lesions on both sequences. Statistical analysis included mixed models with generalized estimating equations, kappa-weighted coefficients and Fisher's exact test.

Results: All lesions demonstrated good conspicuity on VIBE and GRASP sequences (4.28 ± 0.81 versus 3.65 ± 1.22), with no significant difference in lesion detection (P = 0.248). VIBE had slightly higher lesion conspicuity than GRASP for all lesions, with VIBE 12.6% (0.63/5.0) more conspicuous (P < 0.001). Masses and nonmass enhancement (NME) were more conspicuous on VIBE (P < 0.001), with a larger difference for NME (14.2% versus 9.4% more conspicuous). Malignant lesions were more conspicuous than benign lesions (P < 0.001) on both sequences.

Conclusion: GRASP DCE-MRI, a multicoil compressed sensing technique with high spatial resolution and flexible temporal resolution, has near-comparable performance to conventional VIBE imaging for breast lesion evaluation.

Level Of Evidence: 3 Technical Efficacy: Stage 3 J. MAGN. RESON. IMAGING 2017;45:1746-1752.

Citing Articles

FastMRI Breast: A Publicly Available Radial k-Space Dataset of Breast Dynamic Contrast-enhanced MRI.

Solomon E, Johnson P, Tan Z, Tibrewala R, Lui Y, Knoll F Radiol Artif Intell. 2025; 7(1):e240345.

PMID: 39772976 PMC: 11791504. DOI: 10.1148/ryai.240345.

Comparison of golden-angle radial sparse parallel (GRASP) and conventional cartesian sampling in 3D dynamic contrast-enhanced mri for bladder cancer: a preliminary study.

Ueno Y, Sofue K, Tamada T, Takeuchi M, Ebisu N, Nishiuchi K Jpn J Radiol. 2024; 42(12):1469-1478.

PMID: 39088010 PMC: 11588826. DOI: 10.1007/s11604-024-01637-w.

Radiological Biomarkers for Brain Metastases Prognosis: Quantitative Magnetic Resonance Imaging (MRI) Modalities As Non-invasive Biomarkers for the Effect of Radiotherapy.

Eraky A Cureus. 2023; 15(4):e38353.

PMID: 37266043 PMC: 10229388. DOI: 10.7759/cureus.38353.

Impact of Arterial Input Function and Pharmacokinetic Models on DCE-MRI Biomarkers for Detection of Vascular Effect Induced by Stroma-Directed Drug in an Orthotopic Mouse Model of Pancreatic Cancer.

Cao J, Pickup S, Rosen M, Zhou R Mol Imaging Biol. 2023; 25(4):638-647.

PMID: 37166575 DOI: 10.1007/s11307-023-01824-7.

Highly time-resolved 4D MR angiography using golden-angle radial sparse parallel (GRASP) MRI.

Goldman-Yassen A, Raz E, Borja M, Chen D, Derman A, Dogra S Sci Rep. 2022; 12(1):15099.

PMID: 36064872 PMC: 9445093. DOI: 10.1038/s41598-022-18191-y.

References

Schabel M, Morrell G, Oh K, Walczak C, Barlow R, Neumayer L . Pharmacokinetic mapping for lesion classification in dynamic breast MRI. J Magn Reson Imaging. 2010; 31(6):1371-8. PMC: 4657573. DOI: 10.1002/jmri.22179. View

Kuhl C, Schild H, Morakkabati N . Dynamic bilateral contrast-enhanced MR imaging of the breast: trade-off between spatial and temporal resolution. Radiology. 2005; 236(3):789-800. DOI: 10.1148/radiol.2363040811. View

Hargreaves B, Saranathan M, Sung K, Daniel B . Accelerated breast MRI with compressed sensing. Eur J Radiol. 2012; 81 Suppl 1:S54-5. DOI: 10.1016/S0720-048X(12)70020-7. View

Kang S, Ko E, Han B, Shin J, Hahn S, Ko E . Background parenchymal enhancement on breast MRI: influence of menstrual cycle and breast composition. J Magn Reson Imaging. 2013; 39(3):526-34. DOI: 10.1002/jmri.24185. View

Wu X, Raz E, Block T, Geppert C, Hagiwara M, Bruno M . Contrast-enhanced radial 3D fat-suppressed T1-weighted gradient-recalled echo sequence versus conventional fat-suppressed contrast-enhanced T1-weighted studies of the head and neck. AJR Am J Roentgenol. 2014; 203(4):883-9. DOI: 10.2214/AJR.13.11729. View

Chan R, Ramsay E, Cheung E, Plewes D . The influence of radial undersampling schemes on compressed sensing reconstruction in breast MRI. Magn Reson Med. 2011; 67(2):363-77. DOI: 10.1002/mrm.23008. View

Tudorica L, Oh K, Roy N, Kettler M, Chen Y, Hemmingson S . A feasible high spatiotemporal resolution breast DCE-MRI protocol for clinical settings. Magn Reson Imaging. 2012; 30(9):1257-67. PMC: 3466402. DOI: 10.1016/j.mri.2012.04.009. View

Sardanelli F, Rescinito G, Giordano G, Calabrese M, Parodi R . MR dynamic enhancement of breast lesions: high temporal resolution during the first-minute versus eight-minute study. J Comput Assist Tomogr. 2000; 24(5):724-31. DOI: 10.1097/00004728-200009000-00011. View

Feng L, Grimm R, Block K, Chandarana H, Kim S, Xu J . Golden-angle radial sparse parallel MRI: combination of compressed sensing, parallel imaging, and golden-angle radial sampling for fast and flexible dynamic volumetric MRI. Magn Reson Med. 2013; 72(3):707-17. PMC: 3991777. DOI: 10.1002/mrm.24980. View

10.

Mann R, Mus R, van Zelst J, Geppert C, Karssemeijer N, Platel B . A novel approach to contrast-enhanced breast magnetic resonance imaging for screening: high-resolution ultrafast dynamic imaging. Invest Radiol. 2014; 49(9):579-85. DOI: 10.1097/RLI.0000000000000057. View

11.

Leong L, Gombos E, Jagadeesan J, Fook-Chong S . MRI kinetics with volumetric analysis in correlation with hormonal receptor subtypes and histologic grade of invasive breast cancers. AJR Am J Roentgenol. 2015; 204(3):W348-56. PMC: 4851553. DOI: 10.2214/AJR.13.11486. View

12.

El Khouli R, Macura K, Kamel I, Bluemke D, Jacobs M . The effects of applying breast compression in dynamic contrast material-enhanced MR imaging. Radiology. 2014; 272(1):79-90. PMC: 4263656. DOI: 10.1148/radiol.14131384. View

13.

Otazo R, Kim D, Axel L, Sodickson D . Combination of compressed sensing and parallel imaging for highly accelerated first-pass cardiac perfusion MRI. Magn Reson Med. 2010; 64(3):767-76. PMC: 2932824. DOI: 10.1002/mrm.22463. View

14.

Pineda F, Medved M, Wang S, Fan X, Schacht D, Sennett C . Ultrafast Bilateral DCE-MRI of the Breast with Conventional Fourier Sampling: Preliminary Evaluation of Semi-quantitative Analysis. Acad Radiol. 2016; 23(9):1137-44. PMC: 4987200. DOI: 10.1016/j.acra.2016.04.008. View

15.

Rosenkrantz A, Geppert C, Grimm R, Block T, Glielmi C, Feng L . Dynamic contrast-enhanced MRI of the prostate with high spatiotemporal resolution using compressed sensing, parallel imaging, and continuous golden-angle radial sampling: preliminary experience. J Magn Reson Imaging. 2014; 41(5):1365-73. PMC: 4233205. DOI: 10.1002/jmri.24661. View

16.

Buadu L, Murakami J, Murayama S, Hashiguchi N, Sakai S, Masuda K . Breast lesions: correlation of contrast medium enhancement patterns on MR images with histopathologic findings and tumor angiogenesis. Radiology. 1996; 200(3):639-49. DOI: 10.1148/radiology.200.3.8756909. View

17.

Jansen S, Fan X, Karczmar G, Abe H, Schmidt R, Newstead G . Differentiation between benign and malignant breast lesions detected by bilateral dynamic contrast-enhanced MRI: a sensitivity and specificity study. Magn Reson Med. 2008; 59(4):747-54. PMC: 3121098. DOI: 10.1002/mrm.21530. View

18.

Kim S, Feng L, Grimm R, Freed M, Block K, Sodickson D . Influence of temporal regularization and radial undersampling factor on compressed sensing reconstruction in dynamic contrast enhanced MRI of the breast. J Magn Reson Imaging. 2015; 43(1):261-9. PMC: 4666836. DOI: 10.1002/jmri.24961. View

19.

Rossi Espagnet M, Bangiyev L, Haber M, Block K, Babb J, Ruggiero V . High-Resolution DCE-MRI of the Pituitary Gland Using Radial k-Space Acquisition with Compressed Sensing Reconstruction. AJNR Am J Neuroradiol. 2015; 36(8):1444-9. PMC: 4537679. DOI: 10.3174/ajnr.A4324. View

20.

Smith D, Welch E, Li X, Arlinghaus L, Loveless M, Koyama T . Quantitative effects of using compressed sensing in dynamic contrast enhanced MRI. Phys Med Biol. 2011; 56(15):4933-46. PMC: 3192434. DOI: 10.1088/0031-9155/56/15/018. View