» Articles » PMID: 27852095

Naphthoquinones from Onosma Paniculatum with Potential Anti-inflammatory Activity

Overview
Journal Planta Med
Specialty Biology
Date 2016 Nov 17
PMID 27852095
Citations 13
Authors
Affiliations
Soon will be listed here.
Abstract

Four new naphthoquinones (-), including a dimeric one, shikometabolin G (), together with six known ones (-), were isolated from the methanol extract of . Their structures were established based on the analysis of NMR and MS spectroscopic data. All of the compounds were evaluated for inhibitory effects on NO production in murine macrophage RAW 264.7 cells. Compounds , and displayed good activity on the inhibition of NO production (IC = 0.4-16.5 µM), suggesting the potential property of anti-inflammation.

Citing Articles

(A. DC.) Boiss. & Heldr. (Boraginaceae) In Vitro Cultures Targeting Lithospermic Acid B and Rosmarinic Acid Production.

Syklowska-Baranek K, Gawel M, Kuzma L, Wilenska B, Kawka M, Jeziorek M Molecules. 2023; 28(12).

PMID: 37375435 PMC: 10303423. DOI: 10.3390/molecules28124880.


The evaluation of antichagasic and -SARS-CoV-2 potential of inclusion complexes of β- and methyl-β-cyclodextrin with naphthoquinone.

Oliveira V, Silva C, de Freitas Oliveira J, de Sousa da Silva M, Ferreira P, da Siva F J Drug Deliv Sci Technol. 2023; 81:104229.

PMID: 36776572 PMC: 9905044. DOI: 10.1016/j.jddst.2023.104229.


Antiproliferative and cytotoxic effects of bioactive compounds isolated from Onosma bourgaei.

Erenler R, Yildiz I, Aydin A, Genc N Med Oncol. 2022; 39(8):116.

PMID: 35674858 DOI: 10.1007/s12032-022-01705-z.


SK119, a Novel Shikonin Derivative, Leads to Apoptosis in Melanoma Cell Lines and Exhibits Synergistic Effects with Vemurafenib and Cobimetinib.

Kretschmer N, Durchschein C, Hufner A, Rinner B, Lohberger B, Bauer R Int J Mol Sci. 2022; 23(10).

PMID: 35628494 PMC: 9145845. DOI: 10.3390/ijms23105684.


A photochemical and theoretical study of the triplet reactivity of furano- and pyrano-1,4-naphthoquionones towards tyrosine and tryptophan derivatives.

Teixeira R, Goulart J, Correa R, Garden S, Ferreira S, Netto-Ferreira J RSC Adv. 2022; 9(24):13386-13397.

PMID: 35519567 PMC: 9063979. DOI: 10.1039/c9ra01939a.